Hippo/Warts pathway

Reddy BV, Irvine KD. The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation. Development. 2008 Sep;135(17):2827–38. doi: 10.1242/dev.020974. PMID: 18697904.; Saucedo LJ, Edgar BA. Filling out the Hippo pathway. Nature Reviews Molecular Cell Biology. 2007 Aug;8(8):613–21. doi: 10.1038/nrm2221.; Harvey K, Tapon N. The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network. Nat Rev Cancer. 2007 Mar;7(3):182–91. doi: 10.1038/nrc2070. PMID: 17318211.; Edgar BA. From cell structure to transcription: Hippo forges a new path. Cell. 2006 Jan 27;124(2):267–73. doi: 10.1016/j.cell.2006.01.005. PMID: 16439203.

Metabolites

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.7.11.1 non-specific serine/threonine protein kinase ATP:protein phosphotransferase (non-specific)


Proteins

Protein ID name full name