KSRP (KHSRP) binds and destabilizes mRNA

Barreau C, Paillard L, Osborne HB. AU-rich elements and associated factors: are there unifying principles? Nucleic Acids Res. 2005;33(22):7138–50. PMID: 16391004; PMCID: PMC1325018.; Bevilacqua A, Ceriani MC, Capaccioli S, Nicolin A. Post-transcriptional regulation of gene expression by degradation of messenger RNAs. Journal Cellular Physiology. 2003 Mar 31;195(3):356–72. doi: 10.1002/jcp.10272.; Zhang T, Kruys V, Huez G, Gueydan C. AU-rich element-mediated translational control: complexity and multiple activities of trans-activating factors. Biochem Soc Trans. 2002 Nov;30(Pt 6):952–8. doi: 10.1042/bst0300952. PMID: 12440953.

Metabolites

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
3.1.13.4 poly(A)-specific ribonuclease


Proteins

Protein ID name full name