Gastrin-CREB signalling pathway via PKC and MAPK

Grabowska AM, Watson SA. Role of gastrin peptides in carcinogenesis. Cancer Lett. 2007 Nov 08;257(1):1–15. doi: 10.1016/j.canlet.2007.06.017. PMID: 17698287.; de Weerth A, Bläker M, von Schrenck T. [Receptors for cholecystokinin and gastrin]. Z Gastroenterol. 1999 May;37(5):389–401. PMID: 10413847.; Wank SA. Cholecystokinin receptors. American Journal of Physiology-Gastrointestinal and Liver Physiology. 1995 Nov 01;269(5):G628–46. doi: 10.1152/ajpgi.1995.269.5.g628.

Metabolites

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.7.11.13 protein kinase C ATP:protein phosphotransferase (diacylglycerol-dependent)
2.7.11.24 mitogen-activated protein kinase ATP:protein phosphotransferase (MAPKK-activated)
3.6.5.2 small monomeric GTPase GTP phosphohydrolase (cell-regulating)


Proteins

Protein ID name full name