MAP kinase activation
Bardwell AJ, Frankson E, Bardwell L. Selectivity of Docking Sites in MAPK Kinases. Journal of Biological Chemistry. 2009 May;284(19):13165–73. doi: 10.1074/jbc.m900080200.; Banerjee A, Gerondakis S. Coordinating TLR-activated signaling pathways in cells of the immune system. Immunol Cell Biol. 2007 Aug;85(6):420–4. doi: 10.1038/sj.icb.7100098. PMID: 17637696.; Dong C, Davis RJ, Flavell RA. MAP kinases in the immune response. Annu Rev Immunol. 2002;20():55–72. doi: 10.1146/annurev.immunol.20.091301.131133. PMID: 11861597.; Chang L, Karin M. Mammalian MAP kinase signalling cascades. Nature. 2001 Mar 01;410(6824):37–40. doi: 10.1038/35065000. PMID: 11242034.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.3.2.27 | RING-type E3 ubiquitin transferase | [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type) | |
| 2.7.11.1 | non-specific serine/threonine protein kinase | ATP:protein phosphotransferase (non-specific) | |
| 2.7.11.10 | IkappaB kinase | ATP:[IkappaB protein] phosphotransferase | |
| 2.7.11.22 | cyclin-dependent kinase | ATP:cyclin phosphotransferase | |
| 2.7.11.24 | mitogen-activated protein kinase | ATP:protein phosphotransferase (MAPKK-activated) | |
| 2.7.11.25 | mitogen-activated protein kinase kinase kinase | ATP:protein phosphotransferase (MAPKKKK-activated) |
Proteins
| Protein ID | name | full name |
|---|