Signaling by NTRK1 (TRKA)
Huang EJ, Reichardt LF. Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem. 2003;72():609–42. doi: 10.1146/annurev.biochem.72.121801.161629. PMID: 12676795.; Sofroniew MV, Howe CL, Mobley WC. Nerve growth factor signaling, neuroprotection, and neural repair. Annu Rev Neurosci. 2001;24():1217–81. doi: 10.1146/annurev.neuro.24.1.1217. PMID: 11520933.; Kaplan DR, Miller FD. Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol. 2000 Jun;10(3):381–91. doi: 10.1016/s0959-4388(00)00092-1. PMID: 10851172.; Friedman WJ, Greene LA. Neurotrophin signaling via Trks and p75. Exp Cell Res. 1999 Nov 25;253(1):131–42. doi: 10.1006/excr.1999.4705. PMID: 10579918.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.7.11.1 | non-specific serine/threonine protein kinase | ATP:protein phosphotransferase (non-specific) | |
| 2.7.11.24 | mitogen-activated protein kinase | ATP:protein phosphotransferase (MAPKK-activated) | |
| 3.1.3.48 | protein-tyrosine-phosphatase | protein-tyrosine-phosphate phosphohydrolase |
Proteins
| Protein ID | name | full name |
|---|---|---|
| O13453 | pmp1 | Tyrosine-protein phosphatase pmp1 |
| Q09892 | sty1 | Mitogen-activated protein kinase sty1 |
| Q12706 | psk1 | Serine/threonine-protein kinase psk1 |
| Q92398 | spm1 | Mitogen-activated protein kinase spm1 |