Smooth Muscle Contraction

Gunst SJ, Zhang W. Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction. American Journal of Physiology-Cell Physiology. 2008 Sep;295(3):C576–87. doi: 10.1152/ajpcell.00253.2008.; Webb RC. SMOOTH MUSCLE CONTRACTION AND RELAXATION. Advances in Physiology Education. 2003 Dec;27(4):201–6. doi: 10.1152/advances.2003.27.4.201.; Critchley DR. Focal adhesions - the cytoskeletal connection. Curr Opin Cell Biol. 2000 Feb;12(1):133–9. doi: 10.1016/s0955-0674(99)00067-8. PMID: 10679361.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

CO

Formula: CO (27.994915)

CAS ID: 630-08-0

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Nitric oxide

Formula: NO (29.997989)

CAS ID: 10102-43-9

Nitroglycerin

Formula: C3H5N3O9 (227.00258000000002)

CAS ID: 55-63-0

1,2-Dinitroglycerin

Formula: C3H6N2O7 (182.0175006)

CAS ID: 621-65-8

Cinaciguat

Formula: C36H39NO5 (565.2828084)

CAS ID: 329773-35-5

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

3',5'-cyclic GMP(1-)

Formula: C10H11N5O7P (344.0396086)

CAS ID:



Enzyme

EC Number name full name note
1.2.1.3 aldehyde dehydrogenase (NAD+) aldehyde:NAD+ oxidoreductase
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.7.11.18 myosin-light-chain kinase ATP:[myosin light chain] O-phosphotransferase
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase 3',5'-cyclic-GMP 5'-nucleotidohydrolase


Proteins

Protein ID name full name