Ketone body catabolism

Sass JO. Inborn errors of ketogenesis and ketone body utilization. J Inherit Metab Dis. 2012 Jan;35(1):23–8. doi: 10.1007/s10545-011-9324-6. PMID: 21479626.

Metabolites

(R)-3-Hydroxybutanoate

Formula: C4H8O3 (104.0473418)

CAS ID: 625-72-9

Acetoacetate

Formula: C4H6O3 (102.0316926)

CAS ID: 541-50-4

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9



Enzyme

EC Number name full name note
1.1.1.30 3-hydroxybutyrate dehydrogenase (R)-3-hydroxybutanoate:NAD+ oxidoreductase
2.3.1.9 acetyl-CoA C-acetyltransferase acetyl-CoA:acetyl-CoA C-acetyltransferase
2.8.3.5 3-oxoacid CoA-transferase succinyl-CoA:3-oxo-acid CoA-transferase


Proteins

Protein ID name full name