DCC mediated attractive signaling
Round J, Stein E. Netrin signaling leading to directed growth cone steering. Curr Opin Neurobiol. 2007 Feb;17(1):15–21. doi: 10.1016/j.conb.2007.01.003. PMID: 17254765.; Barallobre MJ, Pascual M, Del Río JA, Soriano E. The Netrin family of guidance factors: emphasis on Netrin-1 signalling. Brain Res Brain Res Rev. 2005 Jul;49(1):22–47. doi: 10.1016/j.brainresrev.2004.11.003. PMID: 15960985.; Kruger RP, Lee J, Li W, Guan K. Mapping Netrin Receptor Binding Reveals Domains of Unc5 Regulating Its Tyrosine Phosphorylation. J. Neurosci. 2004 Dec 01;24(48):10826–34. doi: 10.1523/jneurosci.3715-04.2004.; Meriane M, Tcherkezian J, Webber CA, Danek EI, Triki I, McFarlane S, Bloch-Gallego E, Lamarche-Vane N. Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance. J Cell Biol. 2004 Nov 22;167(4):687–98. PMID: 15557120; PMCID: PMC2172574.; Ren XR, Ming GL, Xie Y, Hong Y, Sun DM, Zhao ZQ, Feng Z, Wang Q, Shim S, Chen ZF, Song HJ, Mei L, Xiong WC. Focal adhesion kinase in netrin-1 signaling. Nat Neurosci. 2004 Nov;7(11):1204–12. doi: 10.1038/nn1330. PMID: 15494733.; Li X, Meriane M, Triki I, Shekarabi M, Kennedy TE, Larose L, Lamarche-Vane N. The Adaptor Protein Nck-1 Couples the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) to the Activation of the Small GTPase Rac1 through an Atypical Mechanism. Journal of Biological Chemistry. 2002 Oct;277(40):37788–97. doi: 10.1074/jbc.m205428200.; Shekarabi M, Kennedy TE. The Netrin-1 Receptor DCC Promotes Filopodia Formation and Cell Spreading by Activating Cdc42 and Rac1. Molecular and Cellular Neuroscience. 2002 Jan;19(1):1–17. doi: 10.1006/mcne.2001.1075.; Meyerhardt JA, Caca K, Eckstrand BC, Hu G, Lengauer C, Banavali S, Look AT, Fearon ER. Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas. Cell Growth Differ. 1999 Jan;10(1):35–42. PMID: 9950216.; Keino-Masu K, Masu M, Hinck L, Leonardo ED, Chan SS, Culotti JG, Tessier-Lavigne M. Deleted in Colorectal Cancer (DCC) encodes a netrin receptor. Cell. 1996 Oct 18;87(2):175–85. doi: 10.1016/s0092-8674(00)81336-7. PMID: 8861902.