CDK-mediated phosphorylation and removal of Cdc6
Bell SP, Dutta A. DNA replication in eukaryotic cells. Annu Rev Biochem. 2002;71():333–74. doi: 10.1146/annurev.biochem.71.110601.135425. PMID: 12045100.; Méndez J, Stillman B. Chromatin Association of Human Origin Recognition Complex, Cdc6, and Minichromosome Maintenance Proteins during the Cell Cycle: Assembly of Prereplication Complexes in Late Mitosis. Molecular and Cellular Biology. 2000 Nov 01;20(22):8602–12. doi: 10.1128/mcb.20.22.8602-8612.2000.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 2.3.2.23 | E2 ubiquitin-conjugating enzyme | S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase | |
| 2.3.2.24 | (E3-independent) E2 ubiquitin-conjugating enzyme | S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:L-lysine ubiquitinyl transferase ([E3 ubiquitin transferase]-independent) | |
| 2.7.11.22 | cyclin-dependent kinase | ATP:cyclin phosphotransferase | |
| 2.7.11.23 | [RNA-polymerase]-subunit kinase | ATP:[DNA-directed RNA polymerase] phosphotransferase |
Proteins
| Protein ID | name | full name |
|---|