D-galactosamine and N-acetyl-D-galactosamine degradation

Hu Z, Patel IR, Mukherjee A. Genetic analysis of the roles of agaA, agaI, and agaS genes in the N-acetyl-D-galactosamine and D-galactosamine catabolic pathways in Escherichia coli strains O157:H7 and C. BMC Microbiol. 2013 May 01;13():94. PMID: 23634833; PMCID: PMC3668189.; Leyn SA, Gao F, Yang C, Rodionov DA. N-acetylgalactosamine utilization pathway and regulon in proteobacteria: genomic reconstruction and experimental characterization in Shewanella. J Biol Chem. 2012 Aug 10;287(33):28047–56. PMID: 22711537; PMCID: PMC3431674.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

acetate

Formula: C2H3O2 (59.0133038)

CAS ID: 71-50-1

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
3.5.1.-
2.7.1.11 6-phosphofructokinase ATP:D-fructose-6-phosphate 1-phosphotransferase
4.1.2.40 tagatose-bisphosphate aldolase D-tagatose 1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)


Proteins

Protein ID name full name
P0A797 pfkA ATP-dependent 6-phosphofructokinase isozyme 1
P0AB76 kbaY D-tagatose-1,6-bisphosphate aldolase subunit KbaY
Q8XAC2 agaS D-galactosamine-6-phosphate deaminase AgaS
Q8XAC3 agaA N-acetylgalactosamine-6-phosphate deacetylase