alpha-linolenic acid (ALA) metabolism
Burdge GC. Metabolism of alpha-linolenic acid in humans. Prostaglandins Leukot Essent Fatty Acids. 2006 Sep;75(3):161–8. doi: 10.1016/j.plefa.2006.05.013. PMID: 16828546.; Chen Q, Nilsson Å. Desaturation and chain elongation of n - 3 and n - 6 polyunsaturated fatty acids in the human CaCo-2 cell line. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1993 Feb;1166(2-3):193–201. doi: 10.1016/0005-2760(93)90097-s.
Metabolites
(3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA
Formula: C45H70N7O18P3S (1121.371071)
CAS ID:
(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA
Formula: C45H68N7O17P3S (1103.3605068000002)
CAS ID:
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.3.3.- | |||
| 1.14.19.37 | acyl-CoA 5-desaturase | acyl-CoA,acceptor:oxygen oxidoreductase (5,6 cis-dehydrogenating) | |
| 1.14.19.44 | acyl-CoA (8-3)-desaturase | DELTA8-acyl-CoA,ferrocytochrome b5:oxygen oxidoreductase (5,6-cis-dehydrogenating) | |
| 2.3.1.199 | very-long-chain 3-oxoacyl-CoA synthase | malonyl-CoA:very-long-chain acyl-CoA malonyltransferase (decarboxylating and thioester-hydrolysing) |
Proteins
| Protein ID | name | full name |
|---|