D-galacturonate degradation II
Andberg M, Maaheimo H, Boer H, Penttilä M, Koivula A, Richard P. Characterization of a novel Agrobacterium tumefaciens Galactarolactone Cycloisomerase Enzyme for Direct Conversion of d-Galactarolactone to 3-Deoxy-2-keto-l-threo-hexarate. Journal of Biological Chemistry. 2012 May;287(21):17662–71. doi: 10.1074/jbc.m111.335240.; Richard P, Hilditch S. d-Galacturonic acid catabolism in microorganisms and its biotechnological relevance. Applied Microbiology and Biotechnology. 2009 Jan 22;82(4):597–604. doi: 10.1007/s00253-009-1870-6.
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.1.1.203 | uronate dehydrogenase | uronate:NAD+ 1-oxidoreductase | |
| 5.4.1.4 | D-galactarolactone isomerase | D-galactaro-1,5-lactone isomerase (D-galactaro-1,4-lactone-forming) | |
| 5.5.1.27 | D-galactarolactone cycloisomerase | D-galactaro-1,4-lactone lyase (ring-opening) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| A9CEQ7 | GLI_AGRFC | D-galactarolactone isomerase |
| A9CEQ8 | gci | D-galactarolactone cycloisomerase |
| Q7CRQ0 | udh | Uronate dehydrogenase |
| Q888H1 | PSPTO_1053 | conserved hypothetical protein |