APC/C-mediated degradation of cell cycle proteins
Rape M, Reddy SK, Kirschner MW. The processivity of multiubiquitination by the APC determines the order of substrate degradation. Cell. 2006 Jan 13;124(1):89–103. doi: 10.1016/j.cell.2005.10.032. PMID: 16413484.; Owens TJ, Hoyt MA. The D box asserts itself. Mol Cell. 2005 Jun 10;18(6):611–2. doi: 10.1016/j.molcel.2005.05.019. PMID: 15949434.; FUNG T, POON R. A roller coaster ride with the mitotic cyclins. Seminars in Cell & Developmental Biology. 2005 Jun;16(3):335–42. doi: 10.1016/j.semcdb.2005.02.014.; Castro A, Bernis C, Vigneron S, Labbé JC, Lorca T. The anaphase-promoting complex: a key factor in the regulation of cell cycle. Oncogene. 2005 Jan 13;24(3):314–25. doi: 10.1038/sj.onc.1207973. PMID: 15678131.; Castro A, Vigneron S, Bernis C, Labbé J, Prigent C, Lorca T. The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A. EMBO Reports. 2002 Dec;3(12):1209–14. doi: 10.1093/embo-reports/kvf241.; Peters JM. The anaphase-promoting complex: proteolysis in mitosis and beyond. Mol Cell. 2002 May;9(5):931–43. doi: 10.1016/s1097-2765(02)00540-3. PMID: 12049731.; Burton JL, Solomon MJ. D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p. Genes Dev. 2001 Sep 15;15(18):2381–95. PMID: 11562348; PMCID: PMC312781.; Sørensen CS, Lukas C, Kramer ER, Peters J, Bartek J, Lukas J. A Conserved Cyclin-Binding Domain Determines Functional Interplay between Anaphase-Promoting Complex–Cdh1 and Cyclin A-Cdk2 during Cell Cycle Progression. Molecular and Cellular Biology. 2001 Jun 01;21(11):3692–703. doi: 10.1128/mcb.21.11.3692-3703.2001.; Gieffers C, Dube P, Harris JR, Stark H, Peters JM. Three-dimensional structure of the anaphase-promoting complex. Mol Cell. 2001 Apr;7(4):907–13. doi: 10.1016/s1097-2765(01)00234-9. PMID: 11336713.; Pfleger CM, Kirschner MW. The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev. 2000 Mar 15;14(6):655–65. PMID: 10733526; PMCID: PMC316466.; Zachariae W, Nasmyth K. Whose end is destruction: cell division and the anaphase-promoting complex. Genes Dev. 1999 Aug 15;13(16):2039–58. doi: 10.1101/gad.13.16.2039. PMID: 10465783.; Peters JM. Proteasomes: protein degradation machines of the cell. Trends Biochem Sci. 1994 Sep;19(9):377–82. doi: 10.1016/0968-0004(94)90115-5. PMID: 7985232.