RORA,B,C and NR1D1 (REV-ERBA) regulate gene expression

Laothamatas I, Rasmussen ES, Green CB, Takahashi JS. Metabolic and chemical architecture of the mammalian circadian clock. Cell Chemical Biology. 2023 Sep;30(9):1033–52. doi: 10.1016/j.chembiol.2023.08.014.; Cox KH, Takahashi JS. Circadian clock genes and the transcriptional architecture of the clock mechanism. J Mol Endocrinol. 2019 Nov;63(4):R93–R102. PMID: 31557726; PMCID: PMC6872945.; Duez H, Staels B. The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism. Diabetes and Vascular Disease Research. 2008 Jan 01;5(2):82–8. doi: 10.3132/dvdr.2008.0014.

Metabolites



Enzyme

EC Number name full name note
2.3.1.-
2.3.1.21 carnitine O-palmitoyltransferase palmitoyl-CoA:L-carnitine O-palmitoyltransferase
2.3.1.48 histone acetyltransferase acetyl-CoA:[protein]-L-lysine acetyltransferase
3.5.1.98 histone deacetylase histone amidohydrolase


Proteins

Protein ID name full name