Regulation of Expression and Function of Type I Classical Cadherins

Zhang N, Häring M, Wolf F, Großhans J, Kong D. Dynamics and functions of E-cadherin complexes in epithelial cell and tissue morphogenesis. Mar Life Sci Technol. 2023 Nov 24;5(4):585–601. doi: 10.1007/s42995-023-00206-w.; Gul IS, Hulpiau P, Saeys Y, van Roy F. Evolution and diversity of cadherins and catenins. Exp Cell Res. 2017 Sep 01;358(1):3–9. doi: 10.1016/j.yexcr.2017.03.001. PMID: 28268172.; Bruner HC, Derksen PWB. Loss of E-Cadherin-Dependent Cell–Cell Adhesion and the Development and Progression of Cancer. Cold Spring Harb Perspect Biol. 2017 May 15;10(3):a029330. doi: 10.1101/cshperspect.a029330.; Li G, Pan T, Guo D, Li L. Regulatory Variants and Disease: The E-Cadherin -160C/A SNP as an Example. Molecular Biology International. 2014 Sep 02;2014():1–9. doi: 10.1155/2014/967565.; Brasch J, Harrison OJ, Honig B, Shapiro L. Thinking outside the cell: how cadherins drive adhesion. Trends in Cell Biology. 2012 Jun;22(6):299–310. doi: 10.1016/j.tcb.2012.03.004.

Metabolites

beta-D-Glucose

Formula: C6H12O6 (180.0633852)

CAS ID: 492-61-5

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:



Enzyme

EC Number name full name note
2.1.1.-
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase S-adenosyl-L-methionine:[histone H3]-L-lysine27 N6-methyltransferase
2.1.1.361 [histone H4]-lysine20 N-methyltransferase S-adenosyl-L-methionine:[histone H4]-L-lysine20 N6-methyltransferase
2.3.2.27 RING-type E3 ubiquitin transferase [E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein] ubiquitin transferase (isopeptide bond-forming; RING-type)
2.4.1.109 dolichyl-phosphate-mannose-protein mannosyltransferase dolichyl-phosphate-D-mannose:protein O-D-mannosyltransferase


Proteins

Protein ID name full name