Maturation of TCA enzymes and regulation of TCA cycle

Arnold PK, Finley LWS. Regulation and function of the mammalian tricarboxylic acid cycle. Journal of Biological Chemistry. 2023 Feb;299(2):102838. doi: 10.1016/j.jbc.2022.102838.

Metabolites

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

butenedioate

Formula: C4H2O4 (113.99530920000001)

CAS ID: 17013-01-3



Enzyme

EC Number name full name note
1.16.3.1 ferroxidase Fe(II):oxygen oxidoreductase
1.3.5.1 succinate dehydrogenase succinate:quinone oxidoreductase
4.2.1.3 aconitate hydratase citrate(isocitrate) hydro-lyase (cis-aconitate-forming)


Proteins

Protein ID name full name
P19414 ACO1 Aconitate hydratase, mitochondrial
Q00711 SDH1 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Q07540 YFH1 Frataxin homolog, mitochondrial