Diseases of hemostasis

Castaman G, Matino D. Hemophilia A and B: molecular and clinical similarities and differences. Haematologica. 2019 Aug 08;104(9):1702–9. doi: 10.3324/haematol.2019.221093.; Kaplan AP, Joseph K. Complement, Kinins, and Hereditary Angioedema: Mechanisms of Plasma Instability when C1 Inhibitor is Absent. Clinical Reviews in Allergy & Immunology. 2016 Jun 06;51(2):207–15. doi: 10.1007/s12016-016-8555-6.; Kumar R, Carcao M. Inherited abnormalities of coagulation: hemophilia, von Willebrand disease, and beyond. Pediatr Clin North Am. 2013 Dec;60(6):1419–41. doi: 10.1016/j.pcl.2013.09.002. PMID: 24237980.; Margetic S. Inflammation and haemostasis. Biochem Med (Zagreb). 2012;22(1):49–62. PMID: 22384519; PMCID: PMC4062321.; van Herrewegen F, Meijers JC, Peters M, van Ommen CH. Clinical practice: the bleeding child. Part II: disorders of secondary hemostasis and fibrinolysis. Eur J Pediatr. 2012 Feb;171(2):207–14. PMID: 21922352; PMCID: PMC3258398.; van Ommen CH, Peters M. The bleeding child. Part I: primary hemostatic disorders. Eur J Pediatr. 2012 Jan;171(1):1–10. PMID: 21800040; PMCID: PMC3249149.; Kriz N, Rinder CS, Rinder HM. Physiology of Hemostasis: With Relevance to Current and Future Laboratory Testing. Clinics in Laboratory Medicine. 2009 Jun;29(2):159–74. doi: 10.1016/j.cll.2009.06.004.

Metabolites

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Menatetrenone

Formula: C31H40O2 (444.302814)

CAS ID: 863-61-6



Enzyme

EC Number name full name note
3.4.21.22 coagulation factor IXa
3.4.21.27 coagulation factor XIa
3.4.21.34 plasma kallikrein
3.4.21.38 coagulation factor XIIa
3.4.21.5 thrombin
3.4.21.6 coagulation factor Xa
3.4.24.87 ADAMTS13 endopeptidase
4.1.1.90 peptidyl-glutamate 4-carboxylase peptidyl-glutamate 4-carboxylase (2-methyl-3-phytyl-1,4-naphthoquinone-epoxidizing)


Proteins

Protein ID name full name