Leishmania parasite growth and survival

Mandell MA, Beverley SM. Continual renewal and replication of persistent Leishmania major parasites in concomitantly immune hosts. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E801–10. PMID: 28096392; PMCID: PMC5293024.; Liu D, Uzonna JE. The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response. Front Cell Infect Microbiol. 2012;2():83. PMID: 22919674; PMCID: PMC3417671.

Metabolites

Adenosine

Formula: C10H13N5O4 (267.09674980000005)

CAS ID: 58-61-7

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

GTP(4-)

Formula: C10H12N5O14P3 (518.9593642)

CAS ID: 86527-72-2

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

3',5'-cyclic AMP(1-)

Formula: C10H11N5O6P (328.0446936)

CAS ID: 62906-31-4



Enzyme

EC Number name full name note
2.3.2.2 gamma-glutamyltransferase (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase
2.7.10.2 non-specific protein-tyrosine kinase ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific)
3.4.13.19 membrane dipeptidase
3.4.19.13 glutathione gamma-glutamate hydrolase
3.4.19.14 leukotriene-C4 hydrolase
3.4.21.75 Furin
3.4.24.86 ADAM 17 endopeptidase
3.5.2.6 beta-lactamase beta-lactam hydrolase


Proteins

Protein ID name full name