superpathway of tetrahydrofolate biosynthesis and salvage

Metabolites

7,8-Dihydroneopterin

Formula: C9H13N5O4 (255.0967498)

CAS ID: 1218-98-0

Diphosphate

Formula: H4P2O7 (177.9432294)

CAS ID: 2466-09-3

Glycolaldehyde

Formula: C2H4O2 (60.0211284)

CAS ID: 141-46-8

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

4-aminobenzoate

Formula: C7H6NO2 (136.0398516)

CAS ID: 2906-28-7

6-hydroxymethyl-dihydropterin diphosphate

Formula: C7H8N5O8P2 (351.9848128)

CAS ID:

formate

Formula: CHO2 (44.997654600000004)

CAS ID: 71-47-6

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

ADP(3-)

Formula: C10H12N5O10P2 (424.0059412)

CAS ID:

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+) 5,10-methylenetetrahydrofolate:NADP+ oxidoreductase
3.5.4.16 GTP cyclohydrolase I GTP 7,8-8,9-dihydrolase
3.5.4.9 methenyltetrahydrofolate cyclohydrolase 5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)
6.3.1.21 phosphoribosylglycinamide formyltransferase 2 formate:N1-(5-phospho-beta-D-ribosyl)glycinamide ligase (ADP-forming)


Proteins

Protein ID name full name
Q8NM23 purT PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE
Q8NM84 folE GTP CYCLOHYDROLASE
Q8NSM0 folD METHYLENETETRAHYDROFOLATE DEHYDROGENASE