cyanide detoxification I

Piotrowski M, Volmer JJ. Cyanide metabolism in higher plants: cyanoalanine hydratase is a NIT4 homolog. Plant Mol Biol. 2006 May;61(1-2):111–22. doi: 10.1007/s11103-005-6217-9. PMID: 16786295.; Piotrowski M, Schönfelder S, Weiler EW. The Arabidopsis thaliana isogene NIT4 and its orthologs in tobacco encode beta-cyano-L-alanine hydratase/nitrilase. J Biol Chem. 2001 Jan 26;276(4):2616–21. doi: 10.1074/jbc.m007890200. PMID: 11060302.; Hatzfeld Y, Maruyama A, Schmidt A, Noji M, Ishizawa K, Saito K. beta-Cyanoalanine synthase is a mitochondrial cysteine synthase-like protein in spinach and Arabidopsis. Plant Physiol. 2000 Jul;123(3):1163–71. PMID: 10889265; PMCID: PMC59079.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Hydrogen cyanide

Formula: CHN (27.010898599999997)

CAS ID: 74-90-8

Hydrogen sulfide

Formula: H2S (33.9877212)

CAS ID: 7783-06-4

L-aspartate(1-)

Formula: C4H6NO4 (132.0296816)

CAS ID:



Enzyme

EC Number name full name note
2.5.1.47 cysteine synthase O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase
4.4.1.9 L-3-cyanoalanine synthase L-cysteine hydrogen-sulfide-lyase (adding hydrogen cyanide; L-3-cyanoalanine-forming)


Proteins

Protein ID name full name