superpathway of pyrimidine ribonucleotides de novo biosynthesis
Metabolites
Enzyme
| EC Number | name | full name | note |
|---|---|---|---|
| 1.3.5.2 | dihydroorotate dehydrogenase (quinone) | (S)-dihydroorotate:quinone oxidoreductase | |
| 2.1.3.2 | aspartate carbamoyltransferase | carbamoyl-phosphate:L-aspartate carbamoyltransferase | |
| 2.4.2.10 | orotate phosphoribosyltransferase | orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase | |
| 2.7.4.22 | UMP kinase | ATP:UMP phosphotransferase | |
| 2.7.4.6 | nucleoside-diphosphate kinase | ATP:nucleoside-diphosphate phosphotransferase | |
| 3.5.2.3 | dihydroorotase | (S)-dihydroorotate amidohydrolase | |
| 4.1.1.23 | orotidine-5'-phosphate decarboxylase | orotidine-5'-phosphate carboxy-lyase (UMP-forming) | |
| 6.3.4.16 | carbamoyl-phosphate synthase (ammonia) | carbon-dioxide:ammonia ligase (ADP-forming, carbamate-phosphorylating) | |
| 6.3.4.2 | CTP synthase (glutamine hydrolysing) | UTP:ammonia ligase (ADP-forming) | |
| 6.3.5.5 | carbamoyl-phosphate synthase (glutamine-hydrolysing) | hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating) |
Proteins
| Protein ID | name | full name |
|---|---|---|
| P00968 | carB | Carbamoyl phosphate synthase large chain |
| P05020 | pyrC | Dihydroorotase |
| P08244 | pyrF | Orotidine 5'-phosphate decarboxylase |
| P0A6F1 | carA | Carbamoyl phosphate synthase small chain |
| P0A763 | ndk | Nucleoside diphosphate kinase |
| P0A786 | pyrB | Aspartate carbamoyltransferase catalytic subunit |
| P0A7E1 | pyrD | Dihydroorotate dehydrogenase (quinone) |
| P0A7E3 | pyrE | Orotate phosphoribosyltransferase |
| P0A7E5 | pyrG | CTP synthase |
| P0A7E9 | pyrH | Uridylate kinase |