Calcium cation (BioCAD00000007836)
Metabolite Card
Formula: Ca (39.9626)
SMILES: [Ca++]
Synonyms [en]
calcium(2+); CALCIUM ion; Ca(2+); Ca2+; calcium; calcium(2+) ion
Last reviewed on 2024-06-28.
Cite this Page
Calcium cation. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000007836). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Calcium is essential for the normal growth and maintenance of bones and teeth, and calcium requirements must be met throughout life. Requirements are greatest during periods of growth, such as childhood, during pregnancy and when breast-feeding. Long-term calcium deficiency can lead to osteoporosis, in which the bone deteriorates and there is an increased risk of fractures. Adults need between 1,000 and 1,300 mg of calcium in their daily diet. Calcium is essential for living organisms, particularly in cell physiology, and is the most common metal in many animals. Physiologically, it exists as an ion in the body. Calcium combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Calcium is an important component of a healthy diet. A deficit can affect bone and tooth formation, while overretention can cause kidney stones. Vitamin D is needed to absorb calcium. Dairy products, such as milk and cheese, are a well-known source of calcium. However, some individuals are allergic to dairy products and even more people, particularly those of non-European descent, are lactose-intolerant, leaving them unable to consume dairy products. Fortunately, many other good sources of calcium exist. These include: seaweeds such as kelp, wakame and hijiki; nuts and seeds (like almonds and sesame); beans; amaranth; collard greens; okra; rutabaga; broccoli; kale; and fortified products such as orange juice and soy milk. Calcium has also been found to assist in the production of lymphatic fluids. Furthermore, calcium is found to be associated with primary hypomagnesemia, which is an inborn error of metabolism.
DBLinks
- CAS Registry Number: 14127-61-8
- PubChem CID: 271
- ChEBI: 22984
- HMDB: HMDB0000464
- LipidMaps:
- KEGG: C00076
- BioCyc:
- NCBI MeSH:
- Wikipedia: Calcium
Other DBLinks
- CAS Registry Number: 11079-03-1
- CAS Registry Number: 125302-08-1
- CAS Registry Number: 14127-61-8
- CAS Registry Number: 7440-70-2
- PubChem: 271
- ChEBI: ChEBI:22984
- ChEBI: ChEBI:29108
- HMDB: HMDB0000464
- KEGG: C00076
- Wikipedia: Calcium
- DrugBank: DB01373
- Coconut NaturalProduct: CNP0578859.0
Class / Ontology
- WishartLab ClassyFire: [Homogeneous alkaline earth metal compounds] Homogeneous alkaline earth metal compounds
- ChEBI: [CHEBI:29108] calcium(2+)
- ChEBI: [CHEBI:22984] calcium atom
| ID | EC Number | Name |
|---|---|---|
| Rhea:RHEA:18106 | 7.2.2.10 | Ca2+(in) + ATP + H2O => Ca2+(out) + ADP + phosphate + H+ |
| Rhea:RHEA:18107 | 7.2.2.10 | Ca2+(out) + ADP + phosphate + H+ => Ca2+(in) + ATP + H2O |
| Rhea:RHEA:18108 | 7.2.2.10 | Ca2+(in) + ATP + H2O <=> Ca2+(out) + ADP + phosphate + H+ |
| Rhea:RHEA:24961 | 1.13.12.24 | apo-[aequorin] + coelenterazine + 3 Ca2+ + O2 => excited state-[aequorin] + CO2 |
| Rhea:RHEA:24962 | 1.13.12.24 | excited state-[aequorin] + CO2 => apo-[aequorin] + coelenterazine + 3 Ca2+ + O2 |
| Rhea:RHEA:24963 | 1.13.12.24 | apo-[aequorin] + coelenterazine + 3 Ca2+ + O2 <=> excited state-[aequorin] + CO2 |
| Rhea:RHEA:29256 | Ca2+(in) + Na+(out) => Ca2+(out) + Na+(in) | |
| Rhea:RHEA:29257 | Ca2+(out) + Na+(in) => Ca2+(in) + Na+(out) | |
| Rhea:RHEA:29258 | Ca2+(in) + Na+(out) <=> Ca2+(out) + Na+(in) | |
| Rhea:RHEA:29672 | Ca2+(in) => Ca2+(out) | |
| Rhea:RHEA:29673 | Ca2+(out) => Ca2+(in) | |
| Rhea:RHEA:29674 | Ca2+(in) <=> Ca2+(out) | |
| Rhea:RHEA:55885 | [aequorin] + 3 Ca2+ => [aequorin]—dioxetanone | |
| Rhea:RHEA:55886 | [aequorin]—dioxetanone => [aequorin] + 3 Ca2+ | |
| Rhea:RHEA:55887 | [aequorin] + 3 Ca2+ <=> [aequorin]—dioxetanone | |
| Rhea:RHEA:69956 | Ca2+(in) + 3 Na+(out) => Ca2+(out) + 3 Na+(in) | |
| Rhea:RHEA:69957 | Ca2+(out) + 3 Na+(in) => Ca2+(in) + 3 Na+(out) | |
| Rhea:RHEA:69958 | Ca2+(in) + 3 Na+(out) <=> Ca2+(out) + 3 Na+(in) | |
| Rhea:RHEA:69968 | Ca2+(out) + K+(out) + 4 Na+(in) => Ca2+(in) + K+(in) + 4 Na+(out) | |
| Rhea:RHEA:69969 | Ca2+(in) + K+(in) + 4 Na+(out) => Ca2+(out) + K+(out) + 4 Na+(in) |
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| BioCyc:HUMAN_PWY-6138 | CMP-N-acetylneuraminate biosynthesis I (eukaryotes) |
| BioCyc:HUMAN_PWY-4921 | protein citrullination |
| BioCyc:HUMAN_PWY-6352 | 3-phosphoinositide biosynthesis |
| BioCyc:META_PWY-7150 | polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium) |
| BioCyc:META_PWY-7151 | polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium) |
| BioCyc:META_PWY-7918 | protein N-glycosylation processing phase (yeast) |
| BioCyc:META_PWY-1061 | homogalacturonan biosynthesis |
| BioCyc:META_PWY-3901 | berberine biosynthesis |
| BioCyc:META_BSUBPOLYAMSYN-PWY | spermidine biosynthesis I |
| BioCyc:META_PWY-6352 | 3-phosphoinositide biosynthesis |
| BioCyc:META_PWY-1121 | suberin monomers biosynthesis |
| BioCyc:META_MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS | protein N-glycosylation initial phase (eukaryotic) |
| BioCyc:META_PWY0-1335 | NADH to cytochrome bo oxidase electron transfer I |
| BioCyc:META_LIPA-CORESYN-PWY | Lipid A-core biosynthesis (E. coli K-12) |
| BioCyc:META_PWY-6545 | pyrimidine deoxyribonucleotides de novo biosynthesis III |
| BioCyc:META_PWY-3621 | γ-butyrobetaine degradation |
| BioCyc:META_PWY6666-2 | dopamine degradation |
| BioCyc:META_PWY-7431 | aromatic biogenic amine degradation (bacteria) |
| BioCyc:META_LYSINE-DEG1-PWY | L-lysine degradation XI (mammalian) |
| BioCyc:META_PWY-6507 | 4-deoxy-L-threo-hex-4-enopyranuronate degradation |