Calcium cation (BioCAD00000007836)

blood cerebrospinal fluid (csf) saliva urine

Metabolite Card

Formula: Ca (39.9626)
SMILES: [Ca++]

Synonyms [en]

calcium(2+); CALCIUM ion; Ca(2+); Ca2+; calcium; calcium(2+) ion

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Calcium cation. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000007836). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Calcium is essential for the normal growth and maintenance of bones and teeth, and calcium requirements must be met throughout life. Requirements are greatest during periods of growth, such as childhood, during pregnancy and when breast-feeding. Long-term calcium deficiency can lead to osteoporosis, in which the bone deteriorates and there is an increased risk of fractures. Adults need between 1,000 and 1,300 mg of calcium in their daily diet. Calcium is essential for living organisms, particularly in cell physiology, and is the most common metal in many animals. Physiologically, it exists as an ion in the body. Calcium combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Calcium is an important component of a healthy diet. A deficit can affect bone and tooth formation, while overretention can cause kidney stones. Vitamin D is needed to absorb calcium. Dairy products, such as milk and cheese, are a well-known source of calcium. However, some individuals are allergic to dairy products and even more people, particularly those of non-European descent, are lactose-intolerant, leaving them unable to consume dairy products. Fortunately, many other good sources of calcium exist. These include: seaweeds such as kelp, wakame and hijiki; nuts and seeds (like almonds and sesame); beans; amaranth; collard greens; okra; rutabaga; broccoli; kale; and fortified products such as orange juice and soy milk. Calcium has also been found to assist in the production of lymphatic fluids. Furthermore, calcium is found to be associated with primary hypomagnesemia, which is an inborn error of metabolism.

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 11079-03-1
  • CAS Registry Number: 125302-08-1
  • CAS Registry Number: 14127-61-8
  • CAS Registry Number: 7440-70-2
  • PubChem: 271
  • ChEBI: ChEBI:22984
  • ChEBI: ChEBI:29108
  • HMDB: HMDB0000464
  • KEGG: C00076
  • Wikipedia: Calcium
  • DrugBank: DB01373
  • Coconut NaturalProduct: CNP0578859.0

Class / Ontology

Metabolic Network
ID EC Number Name
Rhea:RHEA:18106 7.2.2.10 Ca2+(in) + ATP + H2O => Ca2+(out) + ADP + phosphate + H+
Rhea:RHEA:18107 7.2.2.10 Ca2+(out) + ADP + phosphate + H+ => Ca2+(in) + ATP + H2O
Rhea:RHEA:18108 7.2.2.10 Ca2+(in) + ATP + H2O <=> Ca2+(out) + ADP + phosphate + H+
Rhea:RHEA:24961 1.13.12.24 apo-[aequorin] + coelenterazine + 3 Ca2+ + O2 => excited state-[aequorin] + CO2
Rhea:RHEA:24962 1.13.12.24 excited state-[aequorin] + CO2 => apo-[aequorin] + coelenterazine + 3 Ca2+ + O2
Rhea:RHEA:24963 1.13.12.24 apo-[aequorin] + coelenterazine + 3 Ca2+ + O2 <=> excited state-[aequorin] + CO2
Rhea:RHEA:29256 Ca2+(in) + Na+(out) => Ca2+(out) + Na+(in)
Rhea:RHEA:29257 Ca2+(out) + Na+(in) => Ca2+(in) + Na+(out)
Rhea:RHEA:29258 Ca2+(in) + Na+(out) <=> Ca2+(out) + Na+(in)
Rhea:RHEA:29672 Ca2+(in) => Ca2+(out)
Rhea:RHEA:29673 Ca2+(out) => Ca2+(in)
Rhea:RHEA:29674 Ca2+(in) <=> Ca2+(out)
Rhea:RHEA:55885 [aequorin] + 3 Ca2+ => [aequorin]—dioxetanone
Rhea:RHEA:55886 [aequorin]—dioxetanone => [aequorin] + 3 Ca2+
Rhea:RHEA:55887 [aequorin] + 3 Ca2+ <=> [aequorin]—dioxetanone
Rhea:RHEA:69956 Ca2+(in) + 3 Na+(out) => Ca2+(out) + 3 Na+(in)
Rhea:RHEA:69957 Ca2+(out) + 3 Na+(in) => Ca2+(in) + 3 Na+(out)
Rhea:RHEA:69958 Ca2+(in) + 3 Na+(out) <=> Ca2+(out) + 3 Na+(in)
Rhea:RHEA:69968 Ca2+(out) + K+(out) + 4 Na+(in) => Ca2+(in) + K+(in) + 4 Na+(out)
Rhea:RHEA:69969 Ca2+(in) + K+(in) + 4 Na+(out) => Ca2+(out) + K+(out) + 4 Na+(in)
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Organism Source

Taxonomy Source

  1. Homo sapiens [ncbi taxid: 9606]

Pathway Synthetic

pathway id name
BioCyc:HUMAN_PWY-6138 CMP-N-acetylneuraminate biosynthesis I (eukaryotes)
BioCyc:HUMAN_PWY-4921 protein citrullination
BioCyc:HUMAN_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:META_PWY-7150 polymethylated quercetin glucoside biosynthesis I - quercetin series (Chrysosplenium)
BioCyc:META_PWY-7151 polymethylated quercetin glucoside biosynthesis II - quercetagetin series (Chrysosplenium)
BioCyc:META_PWY-7918 protein N-glycosylation processing phase (yeast)
BioCyc:META_PWY-1061 homogalacturonan biosynthesis
BioCyc:META_PWY-3901 berberine biosynthesis
BioCyc:META_BSUBPOLYAMSYN-PWY spermidine biosynthesis I
BioCyc:META_PWY-6352 3-phosphoinositide biosynthesis
BioCyc:META_PWY-1121 suberin monomers biosynthesis
BioCyc:META_MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS protein N-glycosylation initial phase (eukaryotic)
BioCyc:META_PWY0-1335 NADH to cytochrome bo oxidase electron transfer I
BioCyc:META_LIPA-CORESYN-PWY Lipid A-core biosynthesis (E. coli K-12)
BioCyc:META_PWY-6545 pyrimidine deoxyribonucleotides de novo biosynthesis III
BioCyc:META_PWY-3621 γ-butyrobetaine degradation
BioCyc:META_PWY6666-2 dopamine degradation
BioCyc:META_PWY-7431 aromatic biogenic amine degradation (bacteria)
BioCyc:META_LYSINE-DEG1-PWY L-lysine degradation XI (mammalian)
BioCyc:META_PWY-6507 4-deoxy-L-threo-hex-4-enopyranuronate degradation
View All Pathways