Dethiobiotin (BioCAD00000009802)
Metabolite Card
Formula: C10H18N2O3 (214.1317)
SMILES: C[C@@H]1NC(=O)N[C@@H]1CCCCCC(O)=O
Synonyms [en]
dethiobiotin; desthiobiotin; d-Dethiobiotin; (+)-Dethiobiotin; 4-Methyl-5-(omega-carboxyamyl)imidazolidone-2; (4R-cis)-5-methyl-2-oxo-4-imidazolidinehexanoic acid
Last reviewed on 2024-06-28.
Cite this Page
Dethiobiotin. 数据之源,洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000009802). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
Dethiobiotin is a synthetic metabolite that mimic the effects of biotin on gene expression and thus have biotin-like activities. In mammals, biotin serves as a coenzyme for carboxylases such as propionyl-CoA carboxylase. (PMID 12730407).
DBLinks
- CAS Registry Number: 533-48-2
- PubChem CID: 445027
- ChEBI: 16691
- HMDB: HMDB0003581
- LipidMaps:
- KEGG: C01909
- BioCyc:
- NCBI MeSH: desthiobiotin
- Wikipedia:
Other DBLinks
- CAS Registry Number: 12022-42-3
- CAS Registry Number: 15720-25-9
- CAS Registry Number: 168252-18-4
- CAS Registry Number: 533-48-2
- CAS Registry Number: 636-20-4
- CAS Registry Number: 6624-58-4
- CAS Registry Number: 85-27-8
- PubChem: 11966269
- PubChem: 445027
- PubChem: 643
- ChEBI: ChEBI:16691
- ChEBI: ChEBI:36990
- ChEBI: ChEBI:37000
- ChEBI: ChEBI:42280
- HMDB: HMDB0003581
- KEGG: C01909
- NCBI MeSH: desthiobiotin
- DrugBank: DB03775
- RefMet: RM0153107
- MoNA: BAF_UVA_POS000453
- MoNA: BAF_UVA_POS000698
- MoNA: BAF_UVA_POS000699
- MoNA: BAF_UVA_POS000700
- MoNA: BAF_UVA_POS000701
- MoNA: CCMSLIB00000578079
- MoNA: CCMSLIB00000578342
- MoNA: CCMSLIB00005463573
- MoNA: CCMSLIB00005463608
- MoNA: CCMSLIB00005463609
- MoNA: CCMSLIB00005463610
- MoNA: CCMSLIB00005720543
- MoNA: EMBL-MCF_spec150043
- MoNA: EMBL-MCF_spec150044
- MoNA: EMBL-MCF_spec150075
- MoNA: EMBL-MCF_spec81653
- MoNA: HMDB0003581_c_ms_1886
- MoNA: KO002731
- MoNA: KO002732
- MoNA: KO002733
- MoNA: KO002734
- MoNA: KO002735
- MoNA: KO009103
- MoNA: KO009104
- MoNA: KO009105
- MoNA: KO009106
- MoNA: MoNA016604
- MoNA: MoNA016696
- MoNA: MoNA016866
- MoNA: MoNA023835
- MoNA: MoNA032456
- MoNA: MoNA032457
- MoNA: MoNA032459
- MoNA: MoNA034513
- MoNA: MoNA034515
- MoNA: MoNA034517
- MoNA: MoNA037305
- MoNA: MoNA038042
- MoNA: MoNA038658
- MoNA: OUF00162
- Metlin: METLIN_3351
- Coconut NaturalProduct: CNP0229365.1
- Coconut NaturalProduct: CNP0545698.1
- Coconut NaturalProduct: CNP0556698.0
- Coconut NaturalProduct: CNP0597565.0
Class / Ontology
- WishartLab ClassyFire: [Fatty acids and conjugates] Fatty acids and conjugates
- RefMet: [Heterocyclic FA] Heterocyclic FA
- ChEBI: [CHEBI:16691] dethiobiotin
- ChEBI: [CHEBI:42280] (4R,5S)-dethiobiotin
- Coconut NaturalProduct: [Wax monoesters] Wax monoesters
- Coconut NaturalProduct: [Imidazole alkaloids] Imidazole alkaloids
- Coconut NaturalProduct: [Phenylpropanoids (C6-C3)] Phenylpropanoids (C6-C3)
| ID | EC Number | Name |
|---|---|---|
| KEGG:R01078 | 2.8.1.6 | dethiobiotin:sulfur sulfurtransferase |
| KEGG:R03182 | 6.3.3.3 | 7,8-diaminononanoate:carbon-dioxide cyclo-ligase |
| KEGG:R12934 | 6.3.3.3 | C22458 + C00002<=>C01909 + C00008 + C00009 |
Taxonomy Source
- Bacillus subtilis [ncbi taxid: 1423]
- Escherichia coli [ncbi taxid: 562]
- Passiflora edulis [ncbi taxid: 78168]
Pathway Synthetic
| pathway id | name |
|---|---|
| PathBank:SMP0000785 | Biotin Metabolism |
| PathBank:SMP0121263 | Biotin Metabolism |