Cystine (BioCAD00000009209)

blood plant natural products microbial natural products

Metabolite Card

Formula: C6H12N2O4S2 (240.0238)
SMILES: NC(CSSCC(N)C(O)=O)C(O)=O

Synonyms [en]

cystine; alpha-Diamino-beta-dithiolactic acid; L-Cystine; Dicysteine; Zystin; cistina

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Cystine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000009209). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A sulfur-containing amino acid obtained by the oxidation of two cysteine molecules which are then linked via a disulfide bond." []

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 23680-84-4
  • CAS Registry Number: 24645-67-8
  • CAS Registry Number: 2680-84-4
  • CAS Registry Number: 349-46-2
  • CAS Registry Number: 56-89-3
  • CAS Registry Number: 6020-39-9
  • CAS Registry Number: 923-32-0
  • PubChem: 3036261
  • PubChem: 595
  • PubChem: 67678
  • PubChem: 6857538
  • ChEBI: ChEBI:17376
  • ChEBI: ChEBI:35494
  • HMDB: HMDB0250712
  • KEGG: C01420
  • BioCyc: cystine
  • NCBI MeSH: Cystine
  • Wikipedia: Cystine
  • DrugBank: DB00138
  • MoNA: BAF_UVA_POS000098
  • MoNA: BAF_UVA_POS000099
  • MoNA: BAF_UVA_POS000100
  • MoNA: BAF_UVA_POS000956
  • MoNA: CCMSLIB00005464452
  • MoNA: CCMSLIB00005464472
  • MoNA: CCMSLIB00005464473
  • MoNA: CCMSLIB00005720335
  • MoNA: CE000595
  • MoNA: CE000596
  • MoNA: CE000597
  • MoNA: CE000598
  • MoNA: CE000599
  • MoNA: CE000600
  • MoNA: CE000601
  • MoNA: CE000602
  • MoNA: CE000603
  • MoNA: EMBL_MCF_2_0_HRMS_Library000014
  • MoNA: EMBL_MCF_2_0_HRMS_Library000370
  • MoNA: FiehnHILIC000291
  • MoNA: FiehnHILIC001135
  • MoNA: FiehnLib000129
  • MoNA: FiehnLib000438
  • MoNA: MoNA002214
  • MoNA: MoNA002215
  • MoNA: MoNA002216
  • MoNA: MoNA016736
  • MoNA: MoNA024272
  • MoNA: MoNA024293
  • MoNA: MoNA032420
  • MoNA: MoNA032425
  • MoNA: MoNA032426
  • MoNA: MoNA037295
  • MoNA: VF-NPL-LTQ007403
  • MoNA: VF-NPL-LTQ007404
  • MoNA: VF-NPL-QEHF025387
  • MoNA: VF-NPL-QEHF025388
  • MoNA: VF-NPL-QEHF025389
  • MoNA: VF-NPL-QEHF025390
  • MoNA: VF-NPL-QEHF025391
  • MoNA: VF-NPL-QEHF025392
  • MoNA: VF-NPL-QEHF025393
  • MoNA: VF-NPL-QEHF025394
  • MoNA: VF-NPL-QEHF025395
  • MoNA: VF-NPL-QEHF025396
  • MoNA: VF-NPL-QEHF025397
  • MoNA: VF-NPL-QEHF025398
  • MoNA: VF-NPL-QEHF025399
  • MoNA: VF-NPL-QEHF025400
  • MoNA: VF-NPL-QEHF025401
  • Metlin: METLIN_63635
  • Coconut NaturalProduct: CNP0036974.0
  • Coconut NaturalProduct: CNP0156303.1
  • Coconut NaturalProduct: CNP0156303.2
  • Coconut NaturalProduct: CNP0156303.3

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R01109 1.8.4.4 glutathione:cystine oxidoreductase
BioCyc:1.8.4.4-RXN 1.8.4.4 L-CYSTINE + 2 GLUTATHIONE --> OXIDIZED-GLUTATHIONE + 2 CYS
BioCyc:TRANS-RXN0-593 7.4.2.12 L-CYSTINE + ATP + WATER --> L-CYSTINE + Pi + PROTON + ADP
BioCyc:TRANS-RXN-285 L-cystine:proton symport
BioCyc:TRANS-RXN-267 transport of cystine
BioCyc:TRANS-RXN-211 cystine/glutamate antiport
BioCyc:TRANS-RXN0-507 CYSTINE --> CYSTINE
BioCyc:CYSTHIOCYS-RXN 4.4.1.35 CYSTINE + WATER --> THIOCYSTEINE + PYRUVATE + AMMONIUM
BioCyc:RXN-15128 CYSTINE<=>2-AMINOACRYLATE + THIOCYSTEINE
BioCyc:TRANS-RXN-331 7.4.2.12 cystine + ATP + WATER --> cystine + ADP + Pi + PROTON
BioCyc:RXN-16657 cystine<=>CPD-17939 + 3 WATER
BioCyc:CYSTINE-REDUCTASE-NADH-RXN 1.8.1.6 PROTON + CYSTINE + NADH --> 2 CYS + NAD
View More
Organism Source

Taxonomy Source

  1. Abelmoschus esculentus [ncbi taxid: 455045]
  2. Actinidia chinensis [ncbi taxid: 3625]
  3. Agaricus bisporus [ncbi taxid: 5341]
  4. Ageratum conyzoides [ncbi taxid: 68299]
  5. Allium ampeloprasum [ncbi taxid: 4681]
  6. Allium cepa [ncbi taxid: 4679]
  7. Allium sativum [ncbi taxid: 4682]
  8. Allium schoenoprasum [ncbi taxid: 74900]
  9. Anacardium occidentale [ncbi taxid: 171929]
  10. Ananas comosus [ncbi taxid: 4615]
  11. Anarhichas lupus [ncbi taxid: 8204]
  12. Anethum graveolens [ncbi taxid: 40922]
  13. Annona cherimola [ncbi taxid: 49314]
  14. Anoplopoma fimbria [ncbi taxid: 229290]
  15. Anthriscus cerefolium [ncbi taxid: 40888]
  16. Apium graveolens [ncbi taxid: 4045]
  17. Arachis hypogaea [ncbi taxid: 3818]
  18. Archosargus probatocephalus [ncbi taxid: 119682]
  19. Arctium lappa [ncbi taxid: 4217]
  20. Armoracia rusticana [ncbi taxid: 3704]
  21. Artocarpus altilis [ncbi taxid: 194251]
  22. Artocarpus heterophyllus [ncbi taxid: 3489]
  23. Asparagus officinalis [ncbi taxid: 4686]
  24. Avena sativa [ncbi taxid: 4498]
  25. Basella alba [ncbi taxid: 3589]
  26. Belone belone [ncbi taxid: 129037]
  27. Bertholletia excelsa [ncbi taxid: 3645]
  28. Beta vulgaris [ncbi taxid: 161934]
  29. Bos taurus [ncbi taxid: 9913]
  30. Brassica juncea [ncbi taxid: 3707]
  31. Brassica napus [ncbi taxid: 3708]
  32. Brassica oleracea [ncbi taxid: 3712]
  33. Brassica rapa [ncbi taxid: 3711]
  34. Brassica ruvo [ncbi taxid: ]
  35. Brosimum alicastrum [ncbi taxid: 194253]
  36. Brosme brosme [ncbi taxid: 81638]
  37. Cajanus cajan [ncbi taxid: 3821]
  38. Camellia sinensis [ncbi taxid: 4442]
  39. Canarium ovatum [ncbi taxid: 43691]
  40. Capra aegagrus [ncbi taxid: 9923]
  41. Capsicum annuum [ncbi taxid: 4072]
  42. Carthamus tinctorius [ncbi taxid: 4222]
  43. Carum carvi [ncbi taxid: 48032]
  44. Carya illinoinensis [ncbi taxid: 32201]
  45. Castanea sativa [ncbi taxid: 21020]
  46. Ceratonia siliqua [ncbi taxid: 20340]
  47. Chanos chanos [ncbi taxid: 29144]
  48. Chenopodium album [ncbi taxid: 3559]
  49. Chenopodium quinoa [ncbi taxid: 63459]
  50. Cicer arietinum [ncbi taxid: 3827]
  51. Cichorium endivia [ncbi taxid: 114280]
  52. Cichorium intybus [ncbi taxid: 13427]
  53. Cinnamomum aromaticum [ncbi taxid: 119260]
  54. Citrullus lanatus [ncbi taxid: 3654]
  55. Citrus latifolia [ncbi taxid: ]
  56. Citrus limon [ncbi taxid: ]
  57. Citrus paradisi [ncbi taxid: ]
  58. Citrus reticulata [ncbi taxid: 85571]
  59. Citrus sinensis [ncbi taxid: 2711]
  60. Cocos nucifera [ncbi taxid: 13894]
  61. Coffea arabica [ncbi taxid: 13443]
  62. Coffea canephora [ncbi taxid: 49390]
  63. Colocasia esculenta [ncbi taxid: 4460]
  64. Corchorus olitorius [ncbi taxid: 93759]
  65. Coregonus artedi [ncbi taxid: 36181]
  66. Coryphaena hippurus [ncbi taxid: 34814]
  67. Crassostrea virginica [ncbi taxid: 6565]
  68. Cucumis melo [ncbi taxid: 3656]
  69. Cucumis sativus [ncbi taxid: 3659]
  70. Cucurbita maxima [ncbi taxid: 3661]
  71. Cucurbita moschata [ncbi taxid: 3662]
  72. Cucurbita pepo [ncbi taxid: 3663]
  73. Cyprinus carpio [ncbi taxid: 7962]
  74. Daucus carota [ncbi taxid: 4039]
  75. Dioscorea pentaphylla [ncbi taxid: 167592]
  76. Diospyros kaki [ncbi taxid: 35925]
  77. Diospyros virginiana [ncbi taxid: 13493]
  78. Eragrostis tef [ncbi taxid: 110835]
  79. Eriobotrya japonica [ncbi taxid: 32224]
  80. Eumetopias jubatus [ncbi taxid: 34886]
  81. Fagopyrum esculentum [ncbi taxid: 3617]
  82. Feijoa sellowiana [ncbi taxid: 260130]
  83. Ficus carica [ncbi taxid: 3494]
  84. Ficus simplicissima [ncbi taxid: 1822162]
  85. Flammulina velutipes [ncbi taxid: 38945]
  86. Foeniculum vulgare [ncbi taxid: ]
  87. Fragaria x ananassa [ncbi taxid: 3747]
  88. Ginkgo biloba [ncbi taxid: 3311]
  89. Glycine max [ncbi taxid: 3847]
  90. Grevillea robusta [ncbi taxid: 105748]
  91. Grifola frondosa [ncbi taxid: 5627]
  92. Helianthus annuus [ncbi taxid: 4232]
  93. Hippoglossus hippoglossus [ncbi taxid: 8267]
  94. Homo sapiens [ncbi taxid: 9606]
  95. Hordeum vulgare [ncbi taxid: 4513]
  96. Ictalurus punctatus [ncbi taxid: 7998]
  97. Ipomoea aquatica [ncbi taxid: 89636]
  98. Ipomoea batatas [ncbi taxid: 4120]
  99. Juglans cinerea [ncbi taxid: 91214]
  100. Juglans nigra [ncbi taxid: 16719]
  101. Juglans regia [ncbi taxid: 51240]
  102. Katsuwonus pelamis [ncbi taxid: 8226]
  103. Lablab purpureus [ncbi taxid: 35936]
  104. Lactuca sativa [ncbi taxid: 4236]
  105. Leiostomus xanthurus [ncbi taxid: 59837]
  106. Lens culinaris [ncbi taxid: 3864]
  107. Lentinus edodes [ncbi taxid: ]
  108. Lepidium sativum [ncbi taxid: 33125]
  109. Linum usitatissimum [ncbi taxid: 4006]
  110. Lophius piscatorius [ncbi taxid: 8074]
  111. Lopholatilus chamaeleonticeps [ncbi taxid: 390349]
  112. Lota lota [ncbi taxid: 69944]
  113. Lupinus albus [ncbi taxid: 3870]
  114. Malus pumila [ncbi taxid: 283210]
  115. Mangifera indica [ncbi taxid: 29780]
  116. Manihot esculenta [ncbi taxid: 3983]
  117. Maranta arundinacea [ncbi taxid: 210060]
  118. Melanogrammus aeglefinus [ncbi taxid: 8056]
  119. Mentha spicata [ncbi taxid: 29719]
  120. Mentha x piperita [ncbi taxid: 34256]
  121. Microstomus kitt [ncbi taxid: 106175]
  122. Molva molva [ncbi taxid: 163112]
  123. Moringa oleifera [ncbi taxid: 3735]
  124. Mus musculus [ncbi taxid: 10090]
  125. Musa acuminata [ncbi taxid: 4641]
  126. Musa x paradisiaca [ncbi taxid: 89151]
  127. Nasturtium officinale [ncbi taxid: 65948]
  128. Nelumbo nucifera [ncbi taxid: 4432]
  129. Nephrops norvegicus [ncbi taxid: 6829]
  130. Ocimum basilicum [ncbi taxid: 39350]
  131. Oenothera biennis [ncbi taxid: 3942]
  132. Oncorhynchus gorbuscha [ncbi taxid: 8017]
  133. Oncorhynchus keta [ncbi taxid: 8018]
  134. Oncorhynchus kisutch [ncbi taxid: 8019]
  135. Oncorhynchus mykiss [ncbi taxid: 8022]
  136. Oncorhynchus nerka [ncbi taxid: 8023]
  137. Oncorhynchus tshawytscha [ncbi taxid: 74940]
  138. Ophiodon elongatus [ncbi taxid: 225387]
  139. Opuntia cochenillifera [ncbi taxid: ]
  140. Origanum vulgare [ncbi taxid: 39352]
  141. Oryza sativa [ncbi taxid: 4530]
  142. Pachyrhizus erosus [ncbi taxid: 109171]
  143. Panicum miliaceum [ncbi taxid: 4540]
  144. Papaver somniferum [ncbi taxid: 3469]
  145. Pastinaca sativa [ncbi taxid: 4041]
  146. Pediomelum esculentum [ncbi taxid: 458363]
  147. Peprilus triacanthus [ncbi taxid: 183653]
  148. Persea americana [ncbi taxid: 3435]
  149. Petroselinum crispum [ncbi taxid: 4043]
  150. Phaseolus lunatus [ncbi taxid: 3884]
  151. Phaseolus vulgaris [ncbi taxid: 3885]
  152. Phoenix dactylifera [ncbi taxid: 42345]
  153. Phyllostachys edulis [ncbi taxid: 38705]
  154. Pinus edulis [ncbi taxid: 3340]
  155. Piper nigrum [ncbi taxid: 13216]
  156. Pistacia vera [ncbi taxid: 55513]
  157. Pisum sativum [ncbi taxid: ]
  158. Pleurotus ostreatus [ncbi taxid: 5322]
  159. Pomatomus saltatrix [ncbi taxid: ]
  160. Porphyra laciniata [ncbi taxid: ]
  161. Portulaca oleracea [ncbi taxid: 46147]
  162. Pouteria sapota [ncbi taxid: 233744]
  163. Prunus armeniaca [ncbi taxid: 36596]
  164. Prunus avium [ncbi taxid: 42229]
  165. Prunus domestica [ncbi taxid: 3758]
  166. Prunus dulcis [ncbi taxid: 3755]
  167. Prunus persica [ncbi taxid: 3760]
  168. Psophocarpus tetragonolobus [ncbi taxid: 3891]
  169. Pyrus communis [ncbi taxid: 23211]
  170. Pyrus pyrifolia [ncbi taxid: 3767]
  171. Raphanus sativus [ncbi taxid: 3726]
  172. Reinhardtius hippoglossoides [ncbi taxid: 111784]
  173. Rheum rhabarbarum [ncbi taxid: 3621]
  174. Rosmarinus officinalis [ncbi taxid: ]
  175. Saccharomyces cerevisiae [ncbi taxid: 4932]
  176. Salmo salar [ncbi taxid: 8030]
  177. Salvia hispanica [ncbi taxid: 49212]
  178. Scophthalmus maximus [ncbi taxid: 52904]
  179. Secale cereale [ncbi taxid: 4550]
  180. Sesamum orientale [ncbi taxid: ]
  181. Sesbania bispinosa [ncbi taxid: 485725]
  182. Sinapis alba [ncbi taxid: 3728]
  183. Solanum lycopersicum [ncbi taxid: 4081]
  184. Solanum melongena [ncbi taxid: 4111]
  185. Solanum tuberosum [ncbi taxid: 4113]
  186. Sorghum bicolor [ncbi taxid: 4558]
  187. Spinacia oleracea [ncbi taxid: 3562]
  188. Stenodus leucichthys [ncbi taxid: 59296]
  189. Stenotomus chrysops [ncbi taxid: 35579]
  190. Sus scrofa [ncbi taxid: 9823]
  191. Syzygium aromaticum [ncbi taxid: 219868]
  192. Theobroma cacao [ncbi taxid: 3641]
  193. Thunnus alalunga [ncbi taxid: 8235]
  194. Thunnus albacares [ncbi taxid: 8236]
  195. Thunnus thynnus [ncbi taxid: 8237]
  196. Thymus vulgaris [ncbi taxid: 49992]
  197. Trigonella foenum-graecum [ncbi taxid: 78534]
  198. Triticosecale rimpaui [ncbi taxid: ]
  199. Triticum aestivum [ncbi taxid: 4565]
  200. Triticum durum [ncbi taxid: ]
  201. Triticum spelta [ncbi taxid: 58933]
  202. Triticum turanicum [ncbi taxid: ]
  203. Undaria pinnatifida [ncbi taxid: 74381]
  204. Vaccinium corymbosum [ncbi taxid: 69266]
  205. Vaccinium macrocarpon [ncbi taxid: 13750]
  206. Valerianella locusta [ncbi taxid: 59166]
  207. Vicia faba [ncbi taxid: 3906]
  208. Vigna aconitifolia [ncbi taxid: 3918]
  209. Vigna angularis [ncbi taxid: 3914]
  210. Vigna mungo [ncbi taxid: 3915]
  211. Vigna radiata [ncbi taxid: 157791]
  212. Vigna unguiculata [ncbi taxid: 3917]
  213. Vitis vinifera [ncbi taxid: 29760]
  214. Xiphias gladius [ncbi taxid: 8245]
  215. Zea mays [ncbi taxid: 4577]
  216. Zingiber officinale [ncbi taxid: 94328]
  217. Allium sativum [ncbi taxid: 4682]

Pathway Synthetic

pathway id name
WikiPathways:WP5029 Amino acid transport defects (IEMs)
WikiPathways:WP4879 Overlap between signal transduction pathways contributing to LMNA laminopathies
WikiPathways:WP4917 Proximal tubule transport
WikiPathways:WP5213 Amino acid metabolism in triple-negative breast cancer cells
WikiPathways:WP4844 Influence of laminopathies on Wnt signaling
WikiPathways:WP4504 Cysteine and methionine catabolism
View All Pathways