Adrenosterone (BioCAD00000005940)

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Metabolite Card

Formula: C19H24O3 (300.1725)
SMILES: [H][C@@]12CCC(=O)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

Synonyms [en]

adrenosterone; Reichstein's substance G; 11-Oxoandrostenedione; 11-oxoandrost-4-ene-3,17-dione; Androst-4-ene-3,11,17-trione; 11-ketoandrostenedione

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Adrenosterone. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000005940). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Adrenosterone is a steroid hormone with weak androgenic effect. It was first isolated in 1936 from the adrenal cortex by Tadeus Reichstein at the Pharmaceutical Institute in the University of Basel. Originally, adrenosterone was called Reichstein's substance G.(Wikipedia). Andrenosterone is created from androst-4-ene-3,17-dione by the work of two enzymes, CYP11B (E1.14.15.4) and 11beta-hydroxysteroid dehydrogenase [EC:1.1.1.146].

Extracellular Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 15407-71-3
  • CAS Registry Number: 382-45-6
  • CAS Registry Number: 82043-34-3
  • CAS Registry Number: 911474-75-4
  • PubChem: 223997
  • PubChem: 9791
  • ChEBI: ChEBI:2495
  • HMDB: HMDB0006772
  • LipidMaps: LMST02020126
  • KEGG: C05285
  • BioCyc: CPD-18926
  • NCBI MeSH: adrenosterone
  • Wikipedia: Adrenosterone
  • RefMet: RM0159789
  • MoNA: Bruker_HCD_library001271
  • MoNA: FiehnHILIC000161
  • MoNA: FiehnHILIC001740
  • MoNA: FiehnLib000073
  • MoNA: FiehnLib000074
  • MoNA: HMDB0006772_c_ms_2188
  • MoNA: VF-NPL-LTQ000259
  • MoNA: VF-NPL-LTQ000260
  • MoNA: VF-NPL-LTQ000261
  • MoNA: VF-NPL-LTQ000262
  • MoNA: VF-NPL-QEHF000532
  • MoNA: VF-NPL-QEHF000533
  • MoNA: VF-NPL-QEHF000534
  • MoNA: VF-NPL-QEHF000535
  • MoNA: VF-NPL-QEHF000536
  • MoNA: VF-NPL-QEHF000537
  • MoNA: VF-NPL-QTOF006522
  • MoNA: VF-NPL-QTOF006523
  • MoNA: VF-NPL-QTOF006524
  • MoNA: VF-NPL-QTOF006525
  • MoNA: VF-NPL-QTOF006526
  • Metlin: METLIN_43200
  • Coconut NaturalProduct: CNP0099156.1
  • Coconut NaturalProduct: CNP0260120.1
  • Coconut NaturalProduct: CNP0260120.2
  • Coconut NaturalProduct: CNP0272450.1
  • Coconut NaturalProduct: CNP0272450.2
  • Coconut NaturalProduct: CNP0272450.3
  • Coconut NaturalProduct: CNP0272450.4
  • Coconut NaturalProduct: CNP0340562.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R04758 1.1.1.146 11beta-hydroxyandrost-4-ene-3,17-dione:NADP+ 11-oxidoreductase
Rhea:RHEA:53485 androst-4-ene-3,11,17-trione + NADPH + H+ => 17β-hydroxyandrost-4-ene-3,11-dione + NADP+
Rhea:RHEA:53486 17β-hydroxyandrost-4-ene-3,11-dione + NADP+ => androst-4-ene-3,11,17-trione + NADPH + H+
Rhea:RHEA:53487 androst-4-ene-3,11,17-trione + NADPH + H+ <=> 17β-hydroxyandrost-4-ene-3,11-dione + NADP+
Rhea:RHEA:69409 11β-hydroxyandrost-4-ene-3,17-dione + NAD+ => androst-4-ene-3,11,17-trione + NADH + H+
Rhea:RHEA:69410 androst-4-ene-3,11,17-trione + NADH + H+ => 11β-hydroxyandrost-4-ene-3,17-dione + NAD+
Rhea:RHEA:69411 11β-hydroxyandrost-4-ene-3,17-dione + NAD+ <=> androst-4-ene-3,11,17-trione + NADH + H+
BioCyc:RXN-22005 1.3.1.22 CPD-18926 + NADPH + PROTON --> CPD-23985 + NADP
BioCyc:RXN-22015 1.1.1.239 CPD-13749 + NAD<=>CPD-18926 + NADH + PROTON
BioCyc:RXN-21983 1.1.1.146 CPD-23964 + NADP<=>CPD-18926 + NADPH + PROTON
BioCyc:RXN-21984 1.1.1.64 CPD-18926 + NADPH + PROTON --> CPD-13749 + NADP
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Organism Source

Taxonomy Source

  1. Mus musculus [ncbi taxid: 10090]

Pathway Synthetic

pathway id name
PathBank:SMP0030406 Androstenedione Metabolism
PathBank:SMP0087530 Androstenedione Metabolism
PathBank:SMP0087421 Androstenedione Metabolism
PathBank:SMP0087364 Androstenedione Metabolism
PathBank:SMP0063688 Androstenedione Metabolism
PathBank:SMP0087271 Androstenedione Metabolism
View All Pathways