7alpha,26-Dihydroxy-4-cholesten-3-one (BioCAD00000005494)

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Metabolite Card

Formula: C27H44O3 (416.329)
SMILES: CC(CO)CCC[C@@H](C)C1CCC2C3[C@H](O)CC4=CC(=O)CC[C@]4(C)C3CC[C@]12C

Synonyms [en]

7alpha,26-dihydroxycholest-4-en-3-one; 4-cholesten-7alpha,26-diol-3-one; 7 alpha,26-Dihydroxy-4-cholesten-3-one; 7,26-Dhxyclso; 7alpha,26-Dihydroxy-4-cholesten-3-one; 7α,27-dihydroxycholestenone

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

7alpha,26-Dihydroxy-4-cholesten-3-one. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000005494). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

7 alpha,26-Dihydroxy-4-cholesten-3-one is involved in primary bile acid biosynthesis. 7 alpha,26-Dihydroxy-4-cholesten-3-one is produced from 7 alpha,27-Dihydroxycholesterol through the action of HSD3B7 (EC:1.1.1.181). 7 alpha,26-Dihydroxy-4-cholesten-3-one can then be converted to 7 alpha-Hydroxy-3-oxo-4-cholestenoate by CYP27A (EC:1.14.13.15).

Extracellular
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 4675-38-1
  • PubChem: 193396
  • PubChem: 53481412
  • ChEBI: ChEBI:190406
  • ChEBI: ChEBI:48825
  • HMDB: HMDB0012459
  • LipidMaps: LMST04030157
  • KEGG: C17336
  • Metlin: METLIN_43144
  • Metlin: METLIN_57919
  • Coconut NaturalProduct: CNP0082291.2

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R08724 1.1.1.181 7alpha,27-dihydroxycholesterol:NAD+ 3-oxidoreductase
KEGG:R08725 C17336 + 2 C00007 + 2 C00005 + 2 C00080<=>C17337 + 2 C00006 + 3 C00001
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
PathBank:SMP0120468 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0000318 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0120697 Familial Hypercholanemia (FHCA)
PathBank:SMP0120463 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0120467 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0120495 Zellweger Syndrome
PathBank:SMP0000035 Bile Acid Biosynthesis
PathBank:SMP0000314 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0000315 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0087329 Bile Acid Biosynthesis
PathBank:SMP0120652 27-Hydroxylase Deficiency
PathBank:SMP0120688 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0120477 Familial Hypercholanemia (FHCA)
PathBank:SMP0000317 Familial Hypercholanemia (FHCA)
PathBank:SMP0087236 Bile Acid Biosynthesis
PathBank:SMP0120683 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0120687 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0120715 Zellweger Syndrome
PathBank:SMP0120871 27-Hydroxylase Deficiency
PathBank:SMP0000316 Zellweger Syndrome
View All Pathways