3beta,7alpha-Dihydroxy-5-cholestenoate (BioCAD00000004138)
Metabolite Card
Formula: C27H44O4 (432.3239)
SMILES: [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C(O)=O
Synonyms [en]
3beta,7alpha-Dihydroxy-5-cholestenoate; 3beta,7alpha-Dihydroxy-5-cholesten-26-oic acid; 3 beta,7 alpha-dihydroxy-5-cholesten-26-oic acid; 3beta,7alpha-dihydroxy-5-cholestenoic acid; 3,7-dihydroxy-5-cholestenoic acid; 3beta,7alpha-Dihydroxy-5-cholesten-26-oate
Last reviewed on 2024-06-28.
Cite this Page
3beta,7alpha-Dihydroxy-5-cholestenoate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000004138). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
3beta,7alpha-Dihydroxy-5-cholestenoate is found in the primary bile acid biosynthesis pathway. It is created from 3beta-Hydroxy-5-cholestenoate through the action of CYP7B (E1.14.13.100). 3beta,7alpha-Dihydroxy-5-cholestenoate is then converted into 7alpha-Hydroxy-3-oxo-4-cholestenoate by the action of HSD3B7 (EC:1.1.1.181).
DBLinks
- CAS Registry Number: 115538-84-6
- PubChem CID: 3081084
- ChEBI: 81015
- HMDB: HMDB0012454
- LipidMaps: LMST04010217
- KEGG: C17335
- BioCyc:
- NCBI MeSH: 3,7-dihydroxy-5-cholestenoic acid
- Wikipedia:
Other DBLinks
- CAS Registry Number: 115538-84-6
- PubChem: 146156528
- PubChem: 3081084
- PubChem: 3082147
- ChEBI: ChEBI:196598
- ChEBI: ChEBI:81015
- HMDB: HMDB0012454
- LipidMaps: LMST04010217
- KEGG: C17335
- NCBI MeSH: 3,7-dihydroxy-5-cholestenoic acid
- RefMet: RM0138911
- Metlin: METLIN_63322
Class / Ontology
- WishartLab ClassyFire: [Bile acids, alcohols and derivatives] Bile acids, alcohols and derivatives
- RefMet: [C27 bile acids] C27 bile acids
- LipidMaps: [C24 bile acids, alcohols, and derivatives [ST0401]] C24 bile acids, alcohols, and derivatives [ST0401]
- ChEBI: [CHEBI:81015] 3beta,7alpha-Dihydroxy-5-cholestenoate
| ID | EC Number | Name |
|---|---|---|
| KEGG:R08727 | 1.14.14.29 | 3beta-hydroxy-5-cholestenoate,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) |
| KEGG:R08728 | 1.1.1.181 | 3beta,7alpha-dihydroxy-5-cholestenoate:NAD+ 3-oxidoreductase |
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP5176 | Disorders of bile acid synthesis and biliary transport |
| PathBank:SMP0120468 | Congenital Bile Acid Synthesis Defect Type III |
| PathBank:SMP0000318 | Congenital Bile Acid Synthesis Defect Type III |
| PathBank:SMP0120697 | Familial Hypercholanemia (FHCA) |
| PathBank:SMP0120463 | Cerebrotendinous Xanthomatosis (CTX) |
| PathBank:SMP0120467 | Congenital Bile Acid Synthesis Defect Type II |
| PathBank:SMP0120495 | Zellweger Syndrome |
| PathBank:SMP0000035 | Bile Acid Biosynthesis |
| PathBank:SMP0000314 | Congenital Bile Acid Synthesis Defect Type II |
| PathBank:SMP0000315 | Cerebrotendinous Xanthomatosis (CTX) |
| PathBank:SMP0087329 | Bile Acid Biosynthesis |
| PathBank:SMP0120652 | 27-Hydroxylase Deficiency |
| PathBank:SMP0120688 | Congenital Bile Acid Synthesis Defect Type III |
| PathBank:SMP0120477 | Familial Hypercholanemia (FHCA) |
| PathBank:SMP0000317 | Familial Hypercholanemia (FHCA) |
| PathBank:SMP0087236 | Bile Acid Biosynthesis |
| PathBank:SMP0120683 | Cerebrotendinous Xanthomatosis (CTX) |
| PathBank:SMP0120687 | Congenital Bile Acid Synthesis Defect Type II |
| PathBank:SMP0120715 | Zellweger Syndrome |
| PathBank:SMP0120871 | 27-Hydroxylase Deficiency |