3',5'-Cyclic diGMP (BioCAD00000004033)

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Metabolite Card

Formula: C20H24N10O14P2 (690.0949)
SMILES: Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@@H](COP(O)(=O)O[C@H]2[C@H]1O)O[C@H]([C@@H]3O)n1cnc2c1nc(N)[nH]c2=O

Synonyms [en]

3',5'-Cyclic diguanylic acid; cdiGMP; Bis-(3',5')-cyclic diGMP; cyclic di-3',5'-guanylate; 3',5'-Cyclic diGMP; guanylyl-(3'->5')-3'-guanylic acid, cyclic 3'->5'''-nucleotide

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

3',5'-Cyclic diGMP. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000004033). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP." []

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 61093-23-0
  • PubChem: 135440063
  • ChEBI: ChEBI:49537
  • KEGG: C16463
  • BioCyc: C-DI-GMP
  • NCBI MeSH: bis(3',5')-cyclic diguanylic acid
  • Wikipedia: Cyclic_di-GMP
  • Metlin: METLIN_71205

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R08057 2.7.7.65 GTP:GTP guanylyltransferase
KEGG:R08991 3.1.4.52 cyclic bis(3->5')diguanylate 3-guanylylhydrolase
BioCyc:RXN0-5359 2.7.7.65 2 GTP --> C-DI-GMP + 2 PPI
BioCyc:RXN0-4181 3.1.4.52 C-DI-GMP + WATER --> PROTON + L-DI-GMP
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
Reactome:R-BTA-168256 Immune System
Reactome:R-BTA-1834949 Cytosolic sensors of pathogen-associated DNA
Reactome:R-BTA-1834941 STING mediated induction of host immune responses
Reactome:R-DME-168256 Immune System
Reactome:R-DME-1834949 Cytosolic sensors of pathogen-associated DNA
Reactome:R-GGA-1834941 STING mediated induction of host immune responses
Reactome:R-MMU-168256 Immune System
Reactome:R-MMU-168249 Innate Immune System
Reactome:R-SSC-168256 Immune System
Reactome:R-XTR-168249 Innate Immune System
Reactome:R-XTR-1834949 Cytosolic sensors of pathogen-associated DNA
Reactome:R-XTR-1834941 STING mediated induction of host immune responses
Reactome:R-BTA-168249 Innate Immune System
Reactome:R-DRE-168256 Immune System
Reactome:R-DRE-1834949 Cytosolic sensors of pathogen-associated DNA
Reactome:R-DRE-1834941 STING mediated induction of host immune responses
Reactome:R-DME-168249 Innate Immune System
Reactome:R-DME-1834941 STING mediated induction of host immune responses
Reactome:R-GGA-168249 Innate Immune System
Reactome:R-RNO-168256 Immune System
View All Pathways