2-(alpha-Hydroxyethyl)thiamine diphosphate (BioCAD00000002240)
Metabolite Card
Formula: C14H23N4O8P2S (469.0712)
SMILES: CC(O)C1=[N+](CC2=CN=C(C)N=C2N)C(C)=C(CCOP(O)(=O)OP(O)(O)=O)S1
Synonyms [en]
2-Hydroxyethyl-ThPP; 2-(alpha-Hydroxyethyl)thiamine diphosphate; 2-(1-hydroxyethyl)thiamine diphosphate; Thiazolium; 2-(a-Hydroxyethyl)thiamine diphosphate; 3-[(4-amino-2-Methyl-5-pyrimidinyl)methyl]-2-(1-hydroxyethyl)-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)- P,p'-dioxide
Last reviewed on 2024-06-28.
Cite this Page
2-(alpha-Hydroxyethyl)thiamine diphosphate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China.
https://biocad_registry.innovation.ac.cn/s/(-)-arctiin
(retrieved
2026-01-03) (CAD Registry RN: BioCAD00000002240). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Note
2-Hydroxyethyl-ThPP is involved in Glycolysis, Gluconeogenesis, Alanine and aspartate matabolism, Valine, Leucine and isoleucine biosynthesis, Pyruvate metabolism, and Butanoate metabolism [Kegg: c05125].
DBLinks
- CAS Registry Number: 10055-47-7
- PubChem CID: 440568
- ChEBI: 978
- HMDB: HMDB0003904
- LipidMaps:
- KEGG: C05125
- BioCyc:
- NCBI MeSH:
- Wikipedia:
Other DBLinks
- CAS Registry Number: 10055-47-7
- PubChem: 440568
- ChEBI: ChEBI:978
- HMDB: HMDB0003904
- KEGG: C05125
- Coconut NaturalProduct: CNP0494307.0
Class / Ontology
- WishartLab ClassyFire: [Pyrimidines and pyrimidine derivatives] Pyrimidines and pyrimidine derivatives
- ChEBI: [CHEBI:978] 2-(1-hydroxyethyl)thiamine diphosphate
- Coconut NaturalProduct: [Pyridine alkaloids] Pyridine alkaloids
| ID | EC Number | Name |
|---|---|---|
| KEGG:R00014 | 1.2.4.1 | pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating) |
| KEGG:R00755 | 4.1.1.1 | C00084 + C00068<=>C05125 |
| KEGG:R03050 | 2.2.1.6 | 2-acetolactate pyruvate-lyase (carboxylating) |
| KEGG:R03270 | 1.2.4.1 | C05125 + C15972<=>C16255 + C00068 |
| KEGG:R04672 | 2.2.1.6 | (S)-2-acetolactate pyruvate-lyase (carboxylating) |
| KEGG:R04673 | 2.2.1.6 | (S)-2-aceto-2-hydroxybutanoate pyruvate-lyase (carboxylating) |
Taxonomy Source
Pathway Synthetic
| pathway id | name |
|---|---|
| WikiPathways:WP1567 | Glycolysis and gluconeogenesis |
| WikiPathways:WP2453 | TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc) |
| WikiPathways:WP3149 | TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc) |
| PathBank:SMP0002355 | Pyruvate Metabolism |