7a,12a-Dihydroxy-cholestene-3-one (BioCAD00000020109)

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Metabolite Card

Formula: C27H44O3 (416.329)
SMILES: [H][C@@]12CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)CC2CC(=O)C=C[C@]12C

Synonyms [en]

7alpha,12alpha-Dihydroxy-cholestene-3-one; 7-a,12-a-Dihydroxycholest-4-en-3-one; 12a-Dihydroxy-cholestene-3-one; 7-a,12-alpha-Dihydroxycholest-4-en-3-one; 7-a,12-alpha-Dihydroxy-4-cholesten-3-one; (7~{R},8~{R},9~{S},10~{R},12~{S},13~{R},14~{S},17~{R})-17-[(1~{R})-1,5-dimethylhexyl]-7,12-dihydroxy-10,13-dimethyl-4,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

7a,12a-Dihydroxy-cholestene-3-one. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000020109). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

7a,12a-Dihydroxy-cholestene-3-one is an intermediate in bile acid synthesis; is considerably higher in patients with cerebrotendinous xanthomatosis (CTX) than in the normal liver. (PMID 7017048).

Extracellular Membrane Mitochondria
Entity Information

DBLinks

Other DBLinks
  • PubChem: 21252277
  • ChEBI: ChEBI:28477
  • HMDB: HMDB0002197
  • KEGG: C05457
  • Coconut NaturalProduct: CNP0365041.1

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
WikiPathways:WP3604 Biochemical pathways: part I
PathBank:SMP0120468 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0000318 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0120697 Familial Hypercholanemia (FHCA)
PathBank:SMP0120463 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0120467 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0120495 Zellweger Syndrome
PathBank:SMP0000035 Bile Acid Biosynthesis
PathBank:SMP0000314 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0000315 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0087329 Bile Acid Biosynthesis
PathBank:SMP0120652 27-Hydroxylase Deficiency
PathBank:SMP0120688 Congenital Bile Acid Synthesis Defect Type III
PathBank:SMP0120477 Familial Hypercholanemia (FHCA)
PathBank:SMP0000317 Familial Hypercholanemia (FHCA)
PathBank:SMP0087236 Bile Acid Biosynthesis
PathBank:SMP0120683 Cerebrotendinous Xanthomatosis (CTX)
PathBank:SMP0120687 Congenital Bile Acid Synthesis Defect Type II
PathBank:SMP0120715 Zellweger Syndrome
PathBank:SMP0120871 27-Hydroxylase Deficiency
View All Pathways