Vinblastine (BioCAD00000019355)

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Metabolite Card

Formula: C46H58N4O9 (810.4204)
SMILES: [H][C@@]12N(C)C3=C(C=C(C(OC)=C3)[C@]3(C[C@@H]4CN(C[C@](O)(CC)C4)CCC4=C3NC3=CC=CC=C43)C(=O)OC)[C@@]11CCN3CC=C[C@@](CC)([C@@H](OC(C)=O)[C@]2(O)C(=O)OC)[C@@]13[H]

Synonyms [en]

vinblastine; Vincaleukoblastine; (+)-vinblastine; Vinblastine Sulfate; Velban; Vinblastina

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Vinblastine. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000019355). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Vinblastine is only found in individuals that have used or taken this drug. It is an antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)The antitumor activity of vinblastine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinblastine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.

Cytoplasm Membrane
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 132142-72-4
  • CAS Registry Number: 143-67-9
  • CAS Registry Number: 72401-36-6
  • CAS Registry Number: 865-21-4
  • PubChem: 129009934
  • PubChem: 133126830
  • PubChem: 13342
  • PubChem: 241903
  • PubChem: 3823887
  • PubChem: 44417235
  • PubChem: 657290
  • PubChem: 6710780
  • PubChem: 73759760
  • ChEBI: ChEBI:125454
  • ChEBI: ChEBI:27375
  • HMDB: HMDB0014710
  • KEGG: C07201
  • KEGG: C11626
  • NCBI MeSH: Vinblastine
  • Wikipedia: Vinblastine
  • DrugBank: DB00570
  • RefMet: RM0136465
  • MoNA: Alkaloids000654
  • MoNA: Bruker_HCD_library000664
  • MoNA: Bruker_HCD_library001602
  • MoNA: CCMSLIB00004680074
  • MoNA: MoNA_0001128
  • MoNA: MoNA_0001129
  • MoNA: MoNA_0001130
  • MoNA: PM000607
  • MoNA: TOF_alkaloids_pos000548
  • MoNA: VF-NPL-QTOF009923
  • MoNA: VF-NPL-QTOF009924
  • MoNA: VF-NPL-QTOF009925
  • Metlin: METLIN_601
  • Metlin: METLIN_69138
  • Coconut NaturalProduct: CNP0155491.1
  • Coconut NaturalProduct: CNP0155491.5
  • Coconut NaturalProduct: CNP0155491.9
  • Coconut NaturalProduct: CNP0305938.1
  • Coconut NaturalProduct: CNP0584906.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R05859 C11641<=>C07201
KEGG:R05860 C07201<=>C07204
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