Sedoheptulose 7-phosphate (BioCAD00000017656)

blood cellular cytoplasm saliva urine fibroblasts placenta

Metabolite Card

Formula: C7H15O10P (290.0403)
SMILES: OC[C@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H](O)[C@@H]1O

Synonyms [en]

Sedoheptulose 7-phosphate; D-Sedoheptulose 7-phosphate; altro-Heptulose 7-phosphate; D-Altro-heptulose 7-phosphate; heptulose-7-phosphate; D-altro-hept-2-ulose 7-phosphate

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Sedoheptulose 7-phosphate. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000017656). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

D-Sedoheptulose 7-phosphate (CAS: 2646-35-7) is an intermediate of the pentose phosphate pathway (PPP) that has two functions: (1) the generation of NADPH for reductive syntheses and oxidative stress responses within cells, and (2) the formation of ribose residues for nucleotide and nucleic acid biosynthesis (PMID: 16055050). It is formed by transketolase and acted upon (degraded) by transaldolase. Sedoheptulose 7-phosphate can be increased in the blood of patients affected with a transaldolase deficiency, a genetic disorder (PMID: 12881455). Sedoheptulose is a ketoheptose, a monosaccharide with seven carbon atoms and a ketone functional group. It is one of the few heptoses found in nature (Wikipedia).

Cytoplasm
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 2646-35-7
  • CAS Registry Number: 89927-08-2
  • PubChem: 165007
  • PubChem: 616
  • PubChem: 92042786
  • ChEBI: ChEBI:133983
  • ChEBI: ChEBI:15721
  • HMDB: HMDB0001068
  • HMDB: HMDB01068
  • HMDB: HMDB0258206
  • KEGG: C05382
  • BioCyc: D-SEDOHEPTULOSE-7-P
  • NCBI MeSH: sedoheptulose 7-phosphate
  • Wikipedia: Sedoheptulose_7-phosphate
  • RefMet: RM0155901
  • MoNA: EMBL_MCF_2_0_HRMS_Library000528
  • MoNA: KO001857
  • MoNA: KO001858
  • MoNA: KO001859
  • MoNA: KO001860
  • MoNA: KO001861
  • Metlin: METLIN_3418
  • Coconut NaturalProduct: CNP0220027.1
  • Coconut NaturalProduct: CNP0568673.1
  • Coconut NaturalProduct: CNP0571481.1
  • Coconut NaturalProduct: CNP0571481.2
  • Coconut NaturalProduct: CNP0578877.1

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R01641 2.2.1.1 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase
KEGG:R01827 2.2.1.2 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase
KEGG:R01843 2.7.1.11 ATP:sedoheptulose 7-phosphate 1-phosphotransferase
KEGG:R01844 2.7.1.14 ATP:sedoheptulose 7-phosphate
KEGG:R01845 3.1.3.11 sedoheptulose 1,7-bisphosphate 1-phosphohydrolase
KEGG:R05645 5.3.1.28 D-glycero-beta-D-manno-heptose-7-phosphate aldose-ketose-isomerase
KEGG:R06590 2.2.1.1 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehydetransferase;
KEGG:R06863 2.2.1.1 D-sedoheptulose-7-phosphate:thiamin diphosphate glycolaldehydetransferase
KEGG:R08575 2.2.1.2 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase
KEGG:R09768 5.3.1.28 D-glycero-D-manno-heptose 7-phosphate aldose-ketose-isomerase
KEGG:R09769 5.3.1.28 D-glycero-alpha-D-manno-heptose 7-phosphate aldose-ketose-isomerase
KEGG:R11326 4.2.3.154 D-sedoheptulose-7-phosphate phosphate-lyase (cyclizing; demethyl-4-deoxygadusol-forming)
KEGG:R11327 4.2.3.155 D-sedoheptulose-7-phosphate phosphate-lyase (cyclizing; 2-epi-valiolone-forming)
BioCyc:1TRANSKETO-RXN 2.2.1.1 D-SEDOHEPTULOSE-7-P + GAP<=>RIBOSE-5P + XYLULOSE-5-PHOSPHATE
BioCyc:RXN0-6541 2.7.1.- D-SEDOHEPTULOSE-7-P + ATP --> PROTON + D-SEDOHEPTULOSE-1-7-P2 + ADP
BioCyc:TRANSALDOL-RXN 2.2.1.2 D-SEDOHEPTULOSE-7-P + GAP<=>FRUCTOSE-6P + ERYTHROSE-4P
BioCyc:RXN0-4301 5.3.1.28 D-SEDOHEPTULOSE-7-P --> D-ALPHABETA-D-HEPTOSE-7-PHOSPHATE
BioCyc:SEDOHEPTULOKINASE-RXN 2.7.1.14 ATP + SEDOHEPTULOSE --> ADP + D-SEDOHEPTULOSE-7-P + PROTON
BioCyc:RXN-22107 2.2.1.- CPD-16501 + ERYTHROSE-4P --> CPD-18718 + D-SEDOHEPTULOSE-7-P
BioCyc:RXN-9583 2.2.1.- 1-deoxy-1-imino-D-erythrose 4-phosphate synthase
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Organism Source

Taxonomy Source

  1. Escherichia coli [ncbi taxid: 562]
  2. Streptomyces hygroscopicus var. limoneus [ncbi taxid: ]

Pathway Synthetic

pathway id name
PlantCyc:SOY_CALVIN-PWY Calvin-Benson-Bassham cycle
PlantCyc:SOY_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch)
PlantCyc:SPIRODELA_PWY-5723 Rubisco shunt
PlantCyc:ACOERULEA_PENTOSE-P-PWY pentose phosphate pathway
PlantCyc:SUNFLOWER_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch) I
PlantCyc:AHALLERI_PWY-5723 Rubisco shunt
PlantCyc:SUNFLOWER_PENTOSE-P-PWY pentose phosphate pathway
PlantCyc:AHALLERI_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch) I
PlantCyc:SVIRIDIS_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch) I
PlantCyc:SWEETORANGE_PWY-5723 Rubisco shunt
PlantCyc:ALYRATA_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch) I
PlantCyc:ALYRATA_CALVIN-PWY Calvin-Benson-Bassham cycle
PlantCyc:ALYRATA_PENTOSE-P-PWY pentose phosphate pathway
PlantCyc:SWITCHGRASS_CALVIN-PWY Calvin-Benson-Bassham cycle
PlantCyc:AMBORELLA_CALVIN-PWY Calvin-Benson-Bassham cycle
PlantCyc:AMBORELLA_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch) I
PlantCyc:TOMATO_PENTOSE-P-PWY pentose phosphate pathway
PlantCyc:ARA_PENTOSE-P-PWY pentose phosphate pathway
PlantCyc:ARA_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch)
PlantCyc:TPARVULA_PWY-5723 Rubisco shunt
View All Pathways