Salicylaldehyde (BioCAD00000017511)

feces

Metabolite Card

Formula: C7H6O2 (122.0368)
SMILES: OC1=CC=CC=C1C=O

Synonyms [en]

salicylaldehyde; 2-hydroxybenzaldehyde; Salicylic aldehyde; Salicylal; o-Formylphenol; Salizylaldehyd

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Salicylaldehyde. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000017511). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

2-Hydroxybenzaldehyde, also known as salicylal or O-formylphenol, belongs to the class of organic compounds known as hydroxybenzaldehydes. These are organic aromatic compounds containing a benzene ring carrying an aldehyde group and a hydroxyl group. 2-Hydroxybenzaldehyde is a cinnamon, cooling, and medical tasting compound. 2-Hydroxybenzaldehyde is found, on average, in the highest concentration within peppermints. 2-Hydroxybenzaldehyde has also been detected, but not quantified, in several different foods, such as common buckwheats, garden tomato (var.), herbs and spices, and tea. This could make 2-hydroxybenzaldehyde a potential biomarker for the consumption of these foods. 2-Hydroxybenzaldehyde is a potentially toxic compound.

Cytoplasm Extracellular
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 27761-48-4
  • CAS Registry Number: 28777-87-9
  • CAS Registry Number: 90-02-8
  • PubChem: 6998
  • ChEBI: ChEBI:16008
  • HMDB: HMDB0034170
  • KEGG: C06202
  • BioCyc: SALICYLALDEHYDE
  • NCBI MeSH: salicylaldehyde
  • Wikipedia: Salicylaldehyde
  • RefMet: RM0135364
  • MoNA: FiehnHILIC000922
  • MoNA: FiehnHILIC002473
  • MoNA: FiehnLib000846
  • MoNA: HMDB0034170_c_ms_101546
  • MoNA: HMDB0034170_c_ms_101547
  • MoNA: HMDB0034170_c_ms_101548
  • MoNA: HMDB0034170_c_ms_101549
  • MoNA: JP004125
  • MoNA: JP005646
  • MoNA: JP008920
  • Metlin: METLIN_66352
  • Coconut NaturalProduct: CNP0132365.0

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R02941 1.2.1.65 salicylaldehyde:NAD+ oxidoreductase
KEGG:R05136 4.1.2.45 (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate hydro-lyase
Rhea:RHEA:18538 1.2.1.65 salicylaldehyde + NAD+ + H2O => salicylate + NADH + 2 H+
Rhea:RHEA:18539 1.2.1.65 salicylate + NADH + 2 H+ => salicylaldehyde + NAD+ + H2O
Rhea:RHEA:18540 1.2.1.65 salicylaldehyde + NAD+ + H2O <=> salicylate + NADH + 2 H+
Rhea:RHEA:27390 4.1.2.45 (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O => salicylaldehyde + pyruvate
Rhea:RHEA:27391 4.1.2.45 salicylaldehyde + pyruvate => (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O
Rhea:RHEA:27392 4.1.2.45 (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O <=> salicylaldehyde + pyruvate
Rhea:RHEA:59009 salicylaldehyde + O2 + H2O => salicylate + H2O2 + H+
Rhea:RHEA:59010 salicylate + H2O2 + H+ => salicylaldehyde + O2 + H2O
Rhea:RHEA:59011 salicylaldehyde + O2 + H2O <=> salicylate + H2O2 + H+
Rhea:RHEA:68881 salicylate + ATP + NADPH + H+ => salicylaldehyde + AMP + diphosphate + NADP+
Rhea:RHEA:68882 salicylaldehyde + AMP + diphosphate + NADP+ => salicylate + ATP + NADPH + H+
Rhea:RHEA:68883 salicylate + ATP + NADPH + H+ <=> salicylaldehyde + AMP + diphosphate + NADP+
Rhea:RHEA:80452 salicyl alcohol + O2 => salicylaldehyde + H2O2
Rhea:RHEA:80453 salicylaldehyde + H2O2 => salicyl alcohol + O2
Rhea:RHEA:80454 salicyl alcohol + O2 <=> salicylaldehyde + H2O2
BioCyc:RXN-8615 4.1.2.45 CPDN-385 + WATER --> SALICYLALDEHYDE + PYRUVATE
BioCyc:RXN-12261 BENZALDEHYDE --> SALICYLALDEHYDE
BioCyc:RXN-18821 2.4.1.- CPD-12575 + SALICYLALDEHYDE --> CPD-20131 + UDP + PROTON
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Organism Source

Taxonomy Source

  1. Anthemis aciphylla BOISS.var.discoidea BOISS [ncbi taxid: ]
  2. Brassica rapa [ncbi taxid: 3711]
  3. Camellia sinensis [ncbi taxid: 4442]
  4. Cinnamomum versum [ncbi taxid: ]
  5. Homo sapiens [ncbi taxid: 9606]
  6. Ligusticum chuanxiong [ncbi taxid: 2689076]
  7. Mentha x piperita [ncbi taxid: 34256]
  8. Pandanus tectorius [ncbi taxid: 4726]

Pathway Synthetic

pathway id name
BioCyc:META_PWY-6954 superpathway of aromatic compound degradation via 2-hydroxypentadienoate
BioCyc:AGRO_PWY-5427 naphthalene degradation (aerobic)
BioCyc:META_PWY-6766 salicin biosynthesis
BioCyc:AURANTIMONAS_PWY-5427 naphthalene degradation (aerobic)
BioCyc:META_PWY-5427 naphthalene degradation (aerobic)
BioCyc:META_PWY-6956 naphthalene degradation to acetyl-CoA
PlantCyc:PLANT_PWY-6766 salicin biosynthesis
PlantCyc:POPLAR_PWY-6763 salicortin biosynthesis
PlantCyc:POPLAR_PWY-6766 salicin biosynthesis
View All Pathways