(+)-epi-Isozizaene (BioCAD00000000171)

microbial natural products

Metabolite Card

Formula: C15H24 (204.1878)
SMILES: C[C@H]1CCC2=C(C)C(C)(C)[C@H]3CC[C@@]12C3

Synonyms [en]

(+)-epi-isozizaene; (3S,3aR,6S)-3,7,7,8-tetramethyl-2,3,4,5,6,7-hexahydro-1H-3a,6-methanoazulene; CYLSPJUZBPWJGC-PJRDJYAKSA-N; epi-isozizaene; (1R,2S,8S)-2,6,7,7-tetramethyltricyclo[6.2.1.0(1,5)]undec-5-ene; 8)undec-3-en

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

(+)-epi-Isozizaene. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000000171). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

(+)-epi-isozizaene is a sesquiterpene. (+)-Epi-isozizaene has been reported in Streptomyces albidoflavus and Streptomyces coelicolor with data available.

Entity Information

DBLinks

Other DBLinks
  • PubChem: 23724686
  • ChEBI: ChEBI:51458
  • KEGG: C16269
  • NCBI MeSH: epi-isozizaene
  • Metlin: METLIN_53537
  • Coconut NaturalProduct: CNP0343020.1
  • Coconut NaturalProduct: CNP0343020.2

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R07830 4.2.3.37 (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-epi-isozizaene-forming]
KEGG:R08851 1.14.15.39 (+)-epi-isozizaene,reduced-ferredoxin:oxygen oxidoreductase (5S-hydroxylating)
KEGG:R08853 1.14.15.39 (+)-epi-isozizaene,reduced-ferredoxin:oxygen oxidoreductase (5R-hydroxylating)
KEGG:R10072 1.14.15.39 (+)-epi-isozizaene,reduced-ferredoxin:oxygen oxidoreductase (5-hydroxylating)
Rhea:RHEA:25977 (+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ => (5S)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Rhea:RHEA:25978 (5S)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => (+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+
Rhea:RHEA:25979 (+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ <=> (5S)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Rhea:RHEA:25985 (+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ => (5R)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Rhea:RHEA:25986 (5R)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => (+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+
Rhea:RHEA:25987 (+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ <=> (5R)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Rhea:RHEA:25993 4.2.3.37 (2E,6E)-farnesyl diphosphate => (+)-epi-isozizaene + diphosphate
Rhea:RHEA:25994 4.2.3.37 (+)-epi-isozizaene + diphosphate => (2E,6E)-farnesyl diphosphate
Rhea:RHEA:25995 4.2.3.37 (2E,6E)-farnesyl diphosphate <=> (+)-epi-isozizaene + diphosphate
Rhea:RHEA:32440 1.14.15.39 (+)-epi-isozizaene + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H+ => albaflavenone + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O
Rhea:RHEA:32441 1.14.15.39 albaflavenone + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O => (+)-epi-isozizaene + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H+
Rhea:RHEA:32442 1.14.15.39 (+)-epi-isozizaene + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H+ <=> albaflavenone + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O
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