FMLP (BioCAD00000011183)

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Metabolite Card

Formula: C21H31N3O5S (437.1984)
SMILES: [H]C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O

Synonyms [en]

FMLP; N-Formyl-L-methionyl-L-leucyl-L-phenylalanine; N-Formyl-methionyl-leucyl-phenylalanine; fMetLeuPhe; fMLF; (2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

FMLP. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000011183). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

A tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor." []

Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 59880-97-6
  • PubChem: 443295
  • ChEBI: ChEBI:53490
  • KEGG: C11596
  • NCBI MeSH: N-Formylmethionine Leucyl-Phenylalanine
  • Wikipedia: N-Formylmethionine-leucyl-phenylalanine
  • Metlin: METLIN_43541

Class / Ontology

Metabolic Network
ID EC Number Name
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
Reactome:R-CFA-162582 Signaling Pathways
Reactome:R-CFA-373076 Class A/1 (Rhodopsin-like receptors)
Reactome:R-CFA-418594 G alpha (i) signalling events
Reactome:R-DRE-372790 Signaling by GPCR
Reactome:R-DRE-444473 Formyl peptide receptors bind formyl peptides and many other ligands
Reactome:R-HSA-500792 GPCR ligand binding
Reactome:R-MMU-162582 Signaling Pathways
Reactome:R-MMU-375276 Peptide ligand-binding receptors
Reactome:R-MMU-388396 GPCR downstream signalling
Reactome:R-RNO-162582 Signaling Pathways
Reactome:R-RNO-372790 Signaling by GPCR
Reactome:R-RNO-444473 Formyl peptide receptors bind formyl peptides and many other ligands
Reactome:R-XTR-373076 Class A/1 (Rhodopsin-like receptors)
Reactome:R-CFA-500792 GPCR ligand binding
Reactome:R-DRE-162582 Signaling Pathways
Reactome:R-DRE-375276 Peptide ligand-binding receptors
Reactome:R-HSA-372790 Signaling by GPCR
Reactome:R-HSA-444473 Formyl peptide receptors bind formyl peptides and many other ligands
Reactome:R-MMU-373076 Class A/1 (Rhodopsin-like receptors)
Reactome:R-MMU-418594 G alpha (i) signalling events
View All Pathways