Etiocholan-3alpha-ol-17-one 3-glucuronide (BioCAD00000010817)

blood urine kidney liver

Metabolite Card

Formula: C25H38O8 (466.2567)
SMILES: [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]2([H])C[C@@H](CC[C@]12C)O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O

Synonyms [en]

Etiocholan-3alpha-ol-17-one 3-glucuronide; 3alpha-hydroxyetiocholan-17-one 3-glucuronide; etiocholanolone glucuronide; 3alpha-hydroxyetiocholan-17-one 3-glucosiduronic acid; 3alpha-Hydroxy-5beta-androstan-17-one 3-glucuronide; 5alpha.-Androstan-3.alpha.-ol-17-one glucoronide

Reviewed

Last reviewed on 2024-06-28.

Cite this Page

Etiocholan-3alpha-ol-17-one 3-glucuronide. 数据之源，洞见之始. SMRUCC genomics institute, a synthetic life researcher from China. https://biocad_registry.innovation.ac.cn/s/(-)-arctiin (retrieved 2026-01-03) (CAD Registry RN: BioCAD00000010817). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

Note

Etiocholanolone glucuronide is a natural human metabolite of etiocholanolone generated in the liver by UDP glucuonyltransferase. Etiocholanolone (or 5-isoandrosterone) is a metabolite of testosterone. Classified a ketosteroid, it causes fever, immunostimulation and leukocytosis. Glucuronidation is used to assist in the excretion of toxic substances, drugs or other substances that cannot be used as an energy source. Glucuronic acid is attached via a glycosidic bond to the substance, and the resulting glucuronide, which has a much higher water solubility than the original substance, is eventually excreted by the kidneys.

Cytoplasm Extracellular Membrane Endoplasmic reticulum
Entity Information

DBLinks

Other DBLinks
  • CAS Registry Number: 3602-09-3
  • PubChem: 443078
  • ChEBI: ChEBI:133504
  • ChEBI: ChEBI:37451
  • HMDB: HMDB0004484
  • LipidMaps: LMST05010014
  • KEGG: C11136
  • NCBI MeSH: androsterone glucuronide
  • Wikipedia: Etiocholanolone glucuronide
  • Wikipedia: Etiocholanolone_glucuronide
  • Metlin: METLIN_43175
  • Coconut NaturalProduct: CNP0123221.1
  • Coconut NaturalProduct: CNP0123221.2

Class / Ontology

Metabolic Network
ID EC Number Name
KEGG:R04352 2.4.1.17 UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)
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Organism Source

Taxonomy Source

Pathway Synthetic

pathway id name
PathBank:SMP0030406 Androstenedione Metabolism
PathBank:SMP0087530 Androstenedione Metabolism
PathBank:SMP0087421 Androstenedione Metabolism
PathBank:SMP0087364 Androstenedione Metabolism
PathBank:SMP0063688 Androstenedione Metabolism
PathBank:SMP0087271 Androstenedione Metabolism
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