EC: 3.4.21.41

complement subcomponent C1r ()

enzyme lambda metabolic reaction experiment
uniprot:P00736 [complement subcomponent C_overbar_1r_(Enzyme) wildtype C1r]

N_Carboxybenzyloxyglycine_L_arginine_thiobenzyl_ester + H2O -> N_Carboxybenzyloxyglycine_L_arginine + Benzylthiol		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 0.01 M HEPES, 0.01 M CaCl2, 9.2 % (v/v) Me2SO
PH: 7.5
Temperature: 30
uniprot:P00736 [complement subcomponent C_overbar_1r_(Enzyme) wildtype C1r]

N_Acetyl_Gly_Lys_methyl_ester + H2O -> Methanol + N_Acetyl_Gly_Lys		 (( (( (kcat * E) ) * S) ) / (S + Km)) buffer: 100 mM K2HPO4, 1.6 U/ml alcohol oxidase, 1 U/ml horseradish peroxidase type VI, 0.5 mg/ml ABTS
PH: 7.5
Temperature: 30

Pathways

pathway id name
Reactome:R-MMU-168256 Immune System
Reactome:R-MMU-168249 Innate Immune System
Reactome:R-MMU-166658 Complement cascade
Reactome:R-MMU-977606 Regulation of Complement cascade
Reactome:R-HSA-168256 Immune System
Reactome:R-HSA-168249 Innate Immune System
Reactome:R-HSA-166658 Complement cascade
Reactome:R-HSA-977606 Regulation of Complement cascade
PathBank:SMP0064047 Classical Complement Pathway
PathBank:SMP0063814 Complement Pathway