cysK - Escherichia coli K-12
Cysteine synthase A
> cysK - Escherichia coli K-12 [Cysteine synthase A]
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Metadata
Organism Source: 83333 - Escherichia coli K-12
EC Number: 2.5.1.47 / 4.5.1.5
Cluster:
Registry Model:
Reactions
| reaction id | name | note |
|---|---|---|
| KEGG:R00897 | O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase; | O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate |
| KEGG:R03601 | O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide) | O-Acetyl-L-serine + Hydrogen selenide <=> L-Selenocysteine + Acetate |
| KEGG:R04003 | 3-chloro-L-alanine chloride-lyase (adding thioglycolate) | 3-Chloro-L-alanine + Thioglycolate <=> S-Carboxymethyl-L-cysteine + Cl- |
| KEGG:R04859 | O3-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase (reducing, L-cysteine-forming); | O-Acetyl-L-serine + Thiosulfate + Thioredoxin + H+ <=> L-Cysteine + Sulfite + Thioredoxin disulfide + Acetate |
| KEGG:R07274 | O-phospho-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase | O-Phospho-L-serine + Hydrogen sulfide <=> L-Cysteine + Orthophosphate |
| BioCyc:ACSERLY-RXN | ACETYLSERINE + HS --> CYS + ACET + PROTON | |
| BioCyc:RXN-12726 | ACETYLSERINE + CPD-678 --> L-SELENOCYSTEINE + ACET + PROTON | |
| Rhea:RHEA:14830 | O-acetyl-L-serine + hydrogen sulfide => L-cysteine + acetate | |
| Rhea:RHEA:14831 | L-cysteine + acetate => O-acetyl-L-serine + hydrogen sulfide | |
| Rhea:RHEA:14832 | O-acetyl-L-serine + hydrogen sulfide <=> L-cysteine + acetate | |
| Rhea:RHEA:22869 | thioglycolate + 3-chloro-L-alanine => S-carboxymethyl-L-cysteine + chloride + H+ | Published in: "S-Carboxymethylcysteine synthase from Escherichia coli." Kumagai, H., Suzuki, H., Shigematsu, H. and Tuchikura, T. Agric. Biol. Chem. 53 (1989) 2481–2487 |
| Rhea:RHEA:22870 | S-carboxymethyl-L-cysteine + chloride + H+ => thioglycolate + 3-chloro-L-alanine | Published in: "S-Carboxymethylcysteine synthase from Escherichia coli." Kumagai, H., Suzuki, H., Shigematsu, H. and Tuchikura, T. Agric. Biol. Chem. 53 (1989) 2481–2487 |
| Rhea:RHEA:22871 | thioglycolate + 3-chloro-L-alanine <=> S-carboxymethyl-L-cysteine + chloride + H+ | Published in: "S-Carboxymethylcysteine synthase from Escherichia coli." Kumagai, H., Suzuki, H., Shigematsu, H. and Tuchikura, T. Agric. Biol. Chem. 53 (1989) 2481–2487 |
| BioCyc:S-CARBOXYMETHYLCYSTEINE-SYNTHASE-RXN | CHLORALAN-CPD + THIOGLYCOLATE<=>PROTON + CPD-44 + CL- |
Pathways
| pathway id | name |
|---|---|
| BioCyc:META_SULFATE-CYS-PWY | superpathway of sulfate assimilation and cysteine biosynthesis |
| BioCyc:ECOL316407_SULFATE-CYS-PWY | superpathway of sulfate assimilation and cysteine biosynthesis |
| BioCyc:ECOL316407_CYSTSYN-PWY | cysteine biosynthesis I |
| BioCyc:META_CYSTSYN-PWY | L-cysteine biosynthesis I |
| BioCyc:ECO_CYSTSYN-PWY | L-cysteine biosynthesis I |
| BioCyc:ECOL316407_LCYSDEG-PWY | L-cysteine degradation II |
| BioCyc:ECO_SULFATE-CYS-PWY | superpathway of sulfate assimilation and cysteine biosynthesis |
| PathBank:SMP0000821 | Cysteine Biosynthesis |
| PathBank:SMP0000939 | Sulfur Metabolism |
| PathBank:SMP0000940 | Sulfur Metabolism (Butanesulfonate) |
| PathBank:SMP0000941 | Sulfur Metabolism (Propanesulfonate) |
| PathBank:SMP0000942 | Sulfur Metabolism (Ethanesulfonate) |
| PathBank:SMP0000943 | Sulfur Metabolism (Isethionate) |
| PathBank:SMP0000944 | Sulfur Metabolism (Methanesulfonate) |
| PathBank:SMP0000993 | Secondary Metabolites: Cysteine Biosynthesis from Serine |