polybrominated phenols biosynthesis

Agarwal V, El Gamal AA, Yamanaka K, Poth D, Kersten RD, Schorn M, Allen EE, Moore BS. Biosynthesis of polybrominated aromatic organic compounds by marine bacteria. Nature Chemical Biology. 2014 Jun 29;10(8):640–7. doi: 10.1038/nchembio.1564.

Metabolites

2,4-Dibromophenol

Formula: C6H4Br2O (249.86288539999998)

CAS ID: 615-58-7

4-Hydroxybenzoate

Formula: C7H6O3 (138.03169259999999)

CAS ID: 99-96-7

Bromide

Formula: Br (78.918336)

CAS ID: 24959-67-9

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8

2,4,6-Tribromophenolate

Formula: C6H2Br3O- (326.76557219999995)

CAS ID:



Enzyme

EC Number name full name note
1.14.19.55 4-hydroxybenzoate brominase (decarboxylating) 4-hydroxybenzoate:NADPH oxidoreductase (brominating, decarboxylating)


Proteins

Protein ID name full name
V4HM83 bmp5 4-hydroxybenzoate brominase (decarboxylating)