GDP-D-perosamine biosynthesis

Albermann C, Piepersberg W. Expression and identification of the RfbE protein from Vibrio cholerae O1 and its use for the enzymatic synthesis of GDP-D-perosamine. Glycobiology. 2001 Aug;11(8):655–61. doi: 10.1093/glycob/11.8.655. PMID: 11479276.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

pyridoxal 5'-phosphate(2-)

Formula: C8H8NO6P (245.0089238)

CAS ID:



Enzyme

EC Number name full name note
2.6.1.102 GDP-perosamine synthase GDP-4-amino-4,6-dideoxy-alpha-D-mannose:2-oxoglutarate aminotransferase
4.2.1.47 GDP-mannose 4,6-dehydratase GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)


Proteins

Protein ID name full name
Q06952 gmd GDP-mannose 4,6-dehydratase
Q06953 rfbE GDP-perosamine synthase