glucosinolate biosynthesis from pentahomomethionine

Sønderby IE, Geu-Flores F, Halkier BA. Biosynthesis of glucosinolates--gene discovery and beyond. Trends Plant Sci. 2010 May;15(5):283–90. doi: 10.1016/j.tplants.2010.02.005. PMID: 20303821.; Geu-Flores F, Nielsen MT, Nafisi M, Møldrup ME, Olsen CE, Motawia MS, Halkier BA. Glucosinolate engineering identifies a gamma-glutamyl peptidase. Nat Chem Biol. 2009 Aug;5(8):575–7. doi: 10.1038/nchembio.185. PMID: 19483696.; Li J, Hansen BG, Ober JA, Kliebenstein DJ, Halkier BA. Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesis. Plant Physiol. 2008 Nov;148(3):1721–33. PMID: 18799661; PMCID: PMC2577257.

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Serylglycine

Formula: C5H10N2O4 (162.064054)

CAS ID: 687-63-8

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8

glucoibarin

Formula: C15H29NO10S3 (479.0953534)

CAS ID: 112572-51-7



Enzyme

EC Number name full name note
4.4.1.-
1.14.13.237 aliphatic glucosinolate S-oxygenase omega-(methylthio)alkyl-glucosinolate,NADPH:oxygen S-oxidoreductase
1.14.14.42 homomethionine N-monooxygenase L-homomethionine,[NADPH-hemoprotein reductase]:oxygen oxidoreductase
2.4.1.195 N-hydroxythioamide S-beta-glucosyltransferase UDP-alpha-D-glucose:N-hydroxy-2-phenylethanethioamide S-beta-D-glucosyltransferase
2.8.2.38 aliphatic desulfoglucosinolate sulfotransferase 3'-phosphoadenylyl-sulfate:aliphatic desulfoglucosinolate sulfotransferase
3.4.19.16 glucosinolate gamma-glutamyl hydrolase


Proteins

Protein ID name full name