rutin biosynthesis

Biesaga M. Influence of extraction methods on stability of flavonoids. J Chromatogr A. 2011 May 06;1218(18):2505–12. doi: 10.1016/j.chroma.2011.02.059. PMID: 21411105.; Kreft S, Strukelj B, Gaberscik A, Kreft I. Rutin in buckwheat herbs grown at different UV-B radiation levels: comparison of two UV spectrophotometric and an HPLC method. J Exp Bot. 2002 Aug;53(375):1801–4. doi: 10.1093/jxb/erf032. PMID: 12147730.; Shen SC, Lee WR, Lin HY, Huang HC, Ko CH, Yang LL, Chen YC. In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production. Eur J Pharmacol. 2002 Jun 20;446(1-3):187–94. doi: 10.1016/s0014-2999(02)01792-2. PMID: 12098601.; Müller K, Ziereis K, Paper DH. Ilex aquifolium: protection against enzymatic and non-enzymatic lipid peroxidation. Planta Med. 1998 Aug;64(6):536–40. doi: 10.1055/s-2006-957509. PMID: 9741300.; Gené RM, Cartaña C, Adzet T, Marín E, Parella T, Cañigueral S. Anti-inflammatory and analgesic activity of Baccharis trimera: identification of its active constituents. Planta Med. 1996 Jun;62(3):232–5. doi: 10.1055/s-2006-957866. PMID: 8693035.; Barber GA, Behrman EJ. The synthesis and characterization of uridine 5'-(ß-l-rhamnopyranosyl diphosphate) and its role in the enzymic synthesis of rutin. Archives of Biochemistry and Biophysics. 1991 Jul;288(1):239–42. doi: 10.1016/0003-9861(91)90190-t.; Iwu MM, Obidoa O, Anazodo M. Biochemical mechanism of the antimalarial activity ofAzadirachta indica leaf extract. Pharmacological Research Communications. 1986 Jan;18(1):81–91. doi: 10.1016/0031-6989(86)90161-x.; Tso TC, Kasperbauer MJ, Sorokin TP. Effect of photoperiod and end-of-day light quality on alkaloids and phenolic compounds of tobacco. Plant Physiol. 1970 Mar;45(3):330–3. PMID: 5423471; PMCID: PMC396407.; Barber GA. The formation of uridine diphosphate l-rhamnose by enzymes of the tobacco leaf. Archives of Biochemistry and Biophysics. 1963 Nov;103(2):276–82. doi: 10.1016/0003-9861(63)90406-5.; BARBER GA. Enzymic glycosylation of quercetin to rutin. Biochemistry. 1962 May 25;1():463–8. doi: 10.1021/bi00909a015. PMID: 13864833.

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Rutin

Formula: C27H30O16 (610.153378)

CAS ID: 153-18-4

2-oxoglutarate(2-)

Formula: C5H4O5 (144.00587339999998)

CAS ID: 64-15-3

succinate(2-)

Formula: C4H4O4 (116.01095839999999)

CAS ID: 56-14-4

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0



Enzyme

EC Number name full name note


Proteins

Protein ID name full name