methylglyoxal degradation I

Marasinghe GPK, Sander IM, Bennett B, Periyannan G, Yang K, Makaroff CA, Crowder MW. Structural Studies on a Mitochondrial Glyoxalase II. Journal of Biological Chemistry. 2005 Dec;280(49):40668–75. doi: 10.1074/jbc.m509748200.; Maiti MK, Krishnasamy S, Owen HA, Makaroff CA. Molecular characterization of glyoxalase II from Arabidopsis thaliana. Plant Mol Biol. 1997 Nov;35(4):471–81. doi: 10.1023/a:1005891123344. PMID: 9349270.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Methylglyoxal

Formula: C3H4O2 (72.0211284)

CAS ID: 78-98-8

Ubiquinone-1

Formula: C14H18O4 (250.1205028)

CAS ID: 727-81-1

QH(2)

Formula: C14H20O4 (252.136152)

CAS ID: 52590-98-4

pyruvate

Formula: C3H3O3 (87.00821880000001)

CAS ID: 57-60-3

Phytochelatin

Formula: C10H16N3O6S- (306.0759776)

CAS ID: 98726-08-0



Enzyme

EC Number name full name note
1.1.2.4 D-lactate dehydrogenase (cytochrome) (R)-lactate:ferricytochrome-c 2-oxidoreductase
3.1.2.6 hydroxyacylglutathione hydrolase S-(2-hydroxyacyl)glutathione hydrolase
4.4.1.5 lactoylglutathione lyase (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing; glutathione-forming)


Proteins

Protein ID name full name