ascorbate recycling (cytosolic)

Linster CL, Van Schaftingen E. Vitamin C. Biosynthesis, recycling and degradation in mammals. FEBS J. 2007 Jan;274(1):1–22. doi: 10.1111/j.1742-4658.2006.05607.x. PMID: 17222174.; Macdonald IK, Badyal SK, Ghamsari L, Moody PCE, Raven EL. Interaction of Ascorbate Peroxidase with Substrates: A Mechanistic and Structural Analysis. Biochemistry. 2006 Jun 01;45(25):7808–17. doi: 10.1021/bi0606849.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

Monodehydroascorbate

Formula: C6H7O6 (175.0242622)

CAS ID:

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADH(2-)

Formula: C21H27N7O14P2 (663.1091182000001)

CAS ID:

NAD(1-)

Formula: C21H26N7O14P2 (662.1012936000001)

CAS ID: 53-84-9

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) 3alpha-hydroxysteroid:NAD(P)+ 3-oxidoreductase (Si-specific)
1.11.1.2 NADPH peroxidase NADPH:hydrogen-peroxide oxidoreductase
1.20.4.2 methylarsonate reductase glutathione:methylarsonate oxidoreductase
1.8.1.9 thioredoxin-disulfide reductase thioredoxin:NADP+ oxidoreductase
1.8.5.1 glutathione dehydrogenase (ascorbate) glutathione:dehydroascorbate oxidoreductase
2.5.1.18 glutathione transferase RX:glutathione R-transferase
5.3.4.1 protein disulfide-isomerase Protein disulfide-isomerase


Proteins

Protein ID name full name