Rapoport-Luebering glycolytic shunt

Cho J, King JS, Qian X, Harwood AJ, Shears SB. Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):5998–6003. PMID: 18413611; PMCID: PMC2329705.; Kauffman KJ, Pajerowski JD, Jamshidi N, Palsson BO, Edwards JS. Description and Analysis of Metabolic Connectivity and Dynamics in the Human Red Blood Cell. Biophysical Journal. 2002 Aug;83(2):646–62. doi: 10.1016/s0006-3495(02)75198-9.; RAPOPORT I, BERGER H, ELSNER R, RAPOPORT S. pH-Dependent Changes of 2,3-Bisphosphoglycerate in Human Red Cells during Transitional and Steady States in vitro. European Journal of Biochemistry. 1977 Mar;73(2):421–7. doi: 10.1111/j.1432-1033.1977.tb11333.x.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

3-phosphonato-D-glyceroyl phosphate(4-)

Formula: C3H4O10P2 (261.9279744)

CAS ID:



Enzyme

EC Number name full name note
3.1.3.62 multiple inositol-polyphosphate phosphatase myo-inositol-hexakisphosphate phosphohydrolase
3.1.3.80 2,3-bisphosphoglycerate 3-phosphatase 2,3-bisphospho-D-glycerate 3-phosphohydrolase
5.4.2.11 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) D-phosphoglycerate 2,3-phosphomutase (2,3-diphosphoglycerate-dependent)
5.4.2.4 Bisphosphoglycerate mutase 3-Phospho-D-glycerate 1,2-phosphomutase


Proteins

Protein ID name full name