flavonoid di-C-glucosylation

Du Y, Chu H, Chu IK, Lo C. CYP93G2 is a flavanone 2-hydroxylase required for C-glycosylflavone biosynthesis in rice. Plant Physiol. 2010 Sep;154(1):324–33. PMID: 20647377; PMCID: PMC2938165.; Brazier-Hicks M, Evans KM, Gershater MC, Puschmann H, Steel PG, Edwards R. The C-Glycosylation of Flavonoids in Cereals. Journal of Biological Chemistry. 2009 Jul;284(27):17926–34. doi: 10.1074/jbc.m109.009258.

Metabolites

CO2

Formula: CO2 (43.98983)

CAS ID: 124-38-9

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Naringenin chalcone

Formula: C15H12O5 (272.0684702)

CAS ID: 25515-46-2

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

p-Coumaroyl-CoA

Formula: C30H42N7O18P3S (913.1519822000001)

CAS ID: 119785-99-8

Phloretin

Formula: C15H14O5 (274.0841194)

CAS ID: 60-82-2

adenosine 5'-monophosphate(2-)

Formula: C10H12N5O7P (345.0474332)

CAS ID:

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

ATP(4-)

Formula: C10H12N5O13P3 (502.9644492)

CAS ID:

UDP-alpha-D-glucose(2-)

Formula: C15H22N2O17P2 (564.0393702)

CAS ID:

UDP(3-)

Formula: C9H11N2O12P2 (400.9787246)

CAS ID: 86527-70-0

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.14.14.162 flavanone 2-hydroxylase flavanone,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (2-hydroxylating)
2.4.1.360 2-hydroxyflavanone C-glucosyltransferase UDP-alpha-D-glucose:2'-hydroxy-beta-oxodihydrochalcone C6/8-beta-D-glucosyltransferase


Proteins

Protein ID name full name