unsaturated, even numbered fatty acid β-oxidation

Graham IA, Eastmond PJ. Pathways of straight and branched chain fatty acid catabolism in higher plants. Prog Lipid Res. 2002 Mar;41(2):156–81. doi: 10.1016/s0163-7827(01)00022-4. PMID: 11755682.; Allenbach L, Poirier Y. Analysis of the alternative pathways for the beta-oxidation of unsaturated fatty acids using transgenic plants synthesizing polyhydroxyalkanoates in peroxisomes. Plant Physiol. 2000 Nov;124(3):1159–68. PMID: 11080293; PMCID: PMC59215.; Engeland K, Kindl H. Evidence for a peroxisomal fatty acid beta-oxidation involving D-3-hydroxyacyl-CoAs. Characterization of two forms of hydro-lyase that convert D-(-)-3-hydroxyacyl-CoA into 2-trans-enoyl-CoA. Eur J Biochem. 1991 Aug 15;200(1):171–8. doi: 10.1111/j.1432-1033.1991.tb21064.x. PMID: 1879422.; ENGELAND K, KINDL H. Purification and characterization of a plant peroxisomal ?2,?3-enoyl-CoA isomerase acting on 3-cis-enoyl-CoA and 3-trans-enoyl-CoA. European Journal of Biochemistry. 1991 Mar;196(3):699–705. doi: 10.1111/j.1432-1033.1991.tb15868.x.; Ji LL, Stratman FW, Lardy HA. Antioxidant enzyme systems in rat liver and skeletal muscle. Influences of selenium deficiency, chronic training, and acute exercise. Arch Biochem Biophys. 1988 May 15;263(1):150–60. doi: 10.1016/0003-9861(88)90623-6. PMID: 3369860.; Behrends W, Thieringer R, Engeland K, Kunau WH, Kindl H. The glyoxysomal beta-oxidation system in cucumber seedlings: identification of enzymes required for the degradation of unsaturated fatty acids. Arch Biochem Biophys. 1988 May 15;263(1):170–7. doi: 10.1016/0003-9861(88)90625-x. PMID: 3369861.; Lindsay DB. Fatty acids as energy sources. Proc Nutr Soc. 1975 Dec;34(3):241–8. doi: 10.1079/pns19750045. PMID: 1108029.

Metabolites

H+

Formula: H (1.0078246)

CAS ID: 12408-02-5

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

NADPH(4-)

Formula: C21H26N7O17P3 (741.0598016)

CAS ID: 53-57-6

NADP(3-)

Formula: C21H25N7O17P3 (740.051977)

CAS ID: 53-59-8



Enzyme

EC Number name full name note
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase (S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase
4.2.1.17 enoyl-CoA hydratase (3S)-3-hydroxyacyl-CoA hydro-lyase
5.1.2.3 3-hydroxybutyryl-CoA epimerase 3-hydroxybutanoyl-CoA 3-epimerase
5.3.3.8 DELTA3-DELTA2-enoyl-CoA isomerase (3Z/3E)-alk-3-enoyl-CoA (2E)-isomerase


Proteins

Protein ID name full name