muropeptide degradation

Park JT, Uehara T. How bacteria consume their own exoskeletons (turnover and recycling of cell wall peptidoglycan). Microbiol Mol Biol Rev. 2008 Jun;72(2):211–27, table of contents. PMID: 18535144; PMCID: PMC2415748.; Uehara T, Park JT. Identification of MpaA, an Amidase in Escherichia coli That Hydrolyzes the ?- d -Glutamyl- meso- Diaminopimelate Bond in Murein Peptides. J Bacteriol. 2003 Jan 15;185(2):679–82. doi: 10.1128/jb.185.2.679-682.2003.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

meso-2,6-Diaminoheptanedioate

Formula: C7H14N2O4 (190.0953524)

CAS ID: 922-54-3

L-alanyl-L-glutamate(1-)

Formula: C8H13N2O5 (217.08244280000002)

CAS ID:



Enzyme

EC Number name full name note
3.4.-.-
3.4.13.18 cytosol nonspecific dipeptidase
3.4.17.13 Muramoyltetrapeptide carboxypeptidase
5.1.1.20 L-Ala-D/L-Glu epimerase L-alanyl-D-glutamate epimerase


Proteins

Protein ID name full name
P0ACV6 mpaA Murein peptide amidase A
P0AFV4 mepS Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase
P15288 pepD Cytosol non-specific dipeptidase
P51981 ycjG L-Ala-D/L-Glu epimerase
P76008 ldcA Murein tetrapeptide carboxypeptidase