nitrilotriacetate degradation

Yuan Z, VanBriesen JM. Bacterial growth yields on EDTA, NTA, and their biodegradation intermediates. Biodegradation. 2008 Feb;19(1):41–52. doi: 10.1007/s10532-007-9113-y. PMID: 17404695.; Egli T. Biodegradation of metal-complexing aminopolycarboxylic acids. Journal of Bioscience and Bioengineering. 2001 Jan;92(2):89–97. doi: 10.1016/s1389-1723(01)80207-3.; Xu Y, Mortimer MW, Fisher TS, Kahn ML, Brockman FJ, Xun L. Cloning, sequencing, and analysis of a gene cluster from Chelatobacter heintzii ATCC 29600 encoding nitrilotriacetate monooxygenase and NADH:flavin mononucleotide oxidoreductase. J Bacteriol. 1997 Feb;179(4):1112–6. doi: 10.1128/jb.179.4.1112-1116.1997.; Knobel HR, Egli T, van der Meer JR. Cloning and characterization of the genes encoding nitrilotriacetate monooxygenase of Chelatobacter heintzii ATCC 29600. J Bacteriol. 1996 Nov;178(21):6123–32. doi: 10.1128/jb.178.21.6123-6132.1996.; Uetz T, Schneider R, Snozzi M, Egli T. Purification and characterization of a two-component monooxygenase that hydroxylates nitrilotriacetate from 'Chelatobacter' strain ATCC 29600. J Bacteriol. 1992 Feb;174(4):1179–88. doi: 10.1128/jb.174.4.1179-1188.1992.

Metabolites

Barium cation

Formula: Ba (137.905236)

CAS ID: 22541-12-4

Calcium cation

Formula: Ca (39.962591)

CAS ID: 14127-61-8

Copper

Formula: Cu (62.929599)

CAS ID: 7440-50-8

Fe2+

Formula: Fe (55.934939)

CAS ID: 15438-31-0

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Magnesium cation

Formula: Mg (23.98505)

CAS ID: 22537-22-0

Manganese(2+)

Formula: Mn (54.938046)

CAS ID: 7439-96-5

Nickel(2+)

Formula: Ni (57.935347)

CAS ID: 14701-22-5

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7

Zinc cation

Formula: Zn (63.929145)

CAS ID: 23713-49-7

potassium cyanide

Formula: CKN (64.966782)

CAS ID: 151-50-8

glyoxylate

Formula: C2HO3 (72.9925696)

CAS ID:

nitrilotriacetate(3-)

Formula: C6H6NO6 (188.0195116)

CAS ID: 28528-44-1

dibromothymoquinone

Formula: C10H10Br2O2 (319.904748)

CAS ID: 29096-93-3



Enzyme

EC Number name full name note
1.14.14.10 nitrilotriacetate monooxygenase nitrilotriacetate,FMNH2:oxygen oxidoreductase (glyoxylate-forming)
1.5.1.42 FMN reductase (NADH) FMNH2:NAD+ oxidoreductase


Proteins

Protein ID name full name
P54989 ntaA Nitrilotriacetate monooxygenase component A
P54990 ntaB FMN reductase (NADH) NtaB