leukotriene biosynthesis

Murphy RC, Gijón MA. Biosynthesis and metabolism of leukotrienes. Biochem J. 2007 Aug 01;405(3):379–95. doi: 10.1042/bj20070289. PMID: 17623009.

Metabolites

H2O

Formula: H2O (18.0105642)

CAS ID: 7732-18-5

Oxygen

Formula: O2 (31.98983)

CAS ID: 7782-44-7



Enzyme

EC Number name full name note
1.13.11.-
1.13.11.34 arachidonate 5-lipoxygenase arachidonate:oxygen 5-oxidoreductase
2.3.2.2 gamma-glutamyltransferase (5-L-glutamyl)-peptide:amino-acid 5-glutamyltransferase
3.3.2.6 leukotriene-A4 hydrolase (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate hydrolase
3.4.11.4 tripeptide aminopeptidase
3.4.13.19 membrane dipeptidase
3.4.19.13 glutathione gamma-glutamate hydrolase
3.4.19.14 leukotriene-C4 hydrolase
3.5.2.6 beta-lactamase beta-lactam hydrolase
4.4.1.20 leukotriene-C4 synthase leukotriene-C4 glutathione-lyase (leukotriene-A4-forming)


Proteins

Protein ID name full name